交感神经切除术对大鼠交感神经诱发腮腺唾液蛋白质组成的影响。

Effects of parasympathectomy on protein composition of sympathetically evoked parotid saliva in rats.

Proctor G B, Asking B, Garrett J R

Department Oral Pathology, King's College School of Medicine & Dentistry, Rayne Institute, London, U.K.

Comp Biochem Physiol A Comp Physiol. 1990;97(3):335-9. doi: 10.1016/0300-9629(90)90620-8.

Abstract

Male Wistar rats were given unilateral postganglionic parasympathectomies by sectioning the auriculo-temporal nerve. 2. Analyses of the protein compositions of sympathetically induced saliva from both glands 1 week later revealed changes in the proportions of different secretory proteins, in particular amylase and basic proline-rich proteins were decreased. 3. These results suggest that parasympathetic impulses are required for the normal synthesis of amylase by parotid parenchyma in rats. Basic proline-rich proteins, known to require a sympathetic drive for normal synthesis, appear to require a parasympathetic input as well.

摘要

通过切断耳颞神经对雄性Wistar大鼠进行单侧节后交感神经切除术。2. 1周后对双侧腺体交感诱导唾液的蛋白质组成进行分析，结果显示不同分泌蛋白的比例发生了变化，尤其是淀粉酶和富含脯氨酸的碱性蛋白减少。3. 这些结果表明，大鼠腮腺实质中淀粉酶的正常合成需要副交感神经冲动。已知富含脯氨酸的碱性蛋白的正常合成需要交感神经驱动，现在看来也需要副交感神经输入。