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阿托品或高频爆发刺激对大鼠腮腺副交感神经唾液成分的影响。

Effects of atropine or high frequency burst excitation on the composition of parasympathetic rat parotid saliva.

作者信息

Ekström J, Månsson B, Tobin G

出版信息

Acta Physiol Scand. 1984 Nov;122(3):409-14. doi: 10.1111/j.1748-1716.1984.tb07526.x.

DOI:10.1111/j.1748-1716.1984.tb07526.x
PMID:6083700
Abstract

In the presence of atropine continuous trains of impulses applied to the auriculo-temporal nerve at relatively high frequencies evoked a flow of parotid saliva that amounted to 5-10% of that before administration of the muscarinic blocker. The output of total protein, amylase, sodium and potassium decreased markedly. However, in terms of concentration protein and amylase increased, while sodium decreased and potassium was unchanged. When, in the absence of atropine, the continuous mode of stimulation was replaced by bursts of impulses of high frequencies the amount of saliva decreased. However, the concentration of protein, amylase and potassium increased, while the concentration of sodium decreased. The findings are discussed in relation to a possible peptidergic innervation of the secretory elements.

摘要

在阿托品存在的情况下,以相对较高频率持续刺激耳颞神经所引发的腮腺唾液分泌量,仅为施用毒蕈碱阻断剂之前唾液分泌量的5% - 10%。总蛋白、淀粉酶、钠和钾的分泌量显著减少。然而,就浓度而言,蛋白和淀粉酶增加,钠减少,钾不变。在没有阿托品的情况下,当将连续刺激模式替换为高频脉冲串刺激时,唾液分泌量减少。然而,蛋白、淀粉酶和钾的浓度增加,而钠的浓度降低。结合分泌细胞可能存在的肽能神经支配对这些发现进行了讨论。

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Effects of atropine or high frequency burst excitation on the composition of parasympathetic rat parotid saliva.阿托品或高频爆发刺激对大鼠腮腺副交感神经唾液成分的影响。
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引用本文的文献

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J Physiol. 1993 Dec;472:233-44. doi: 10.1113/jphysiol.1993.sp019944.
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J Physiol. 1988 Sep;403:105-16. doi: 10.1113/jphysiol.1988.sp017241.
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Submandibular responses to stimulation of the parasympathetic innervation in bursts in the anaesthetized ferret.
麻醉雪貂中,下颌下腺对副交感神经支配以脉冲形式刺激的反应。
J Physiol. 1990 Dec;431:417-25. doi: 10.1113/jphysiol.1990.sp018337.