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猪链球菌致真菌性腹主动脉瘤 1 例报告。

Mycotic abdominal aortic aneurysm due to Streptococcus suis: a case report.

机构信息

Division of Vascular and Endovascular Surgery, Department of Surgery, Chiang Mai University Hospital, Chiang Mai, Thailand.

出版信息

Surg Infect (Larchmt). 2010 Apr;11(2):179-81. doi: 10.1089/sur.2008.111.

Abstract

BACKGROUND

Streptococcus suis is a common infection of pigs. Human infection is often related to accidental inoculation through skin injuries during occupational exposure to pigs and pork. The disease may present as meningitis, bacteremia, and less commonly endocarditis, arthritis, or bronchopneumonia.

METHODS

Case report and review of the literature.

RESULTS

We report a case of bacteremia and severe sepsis caused by S. suis serotype 2 complicated by septic arthritis in a 56-year-old male with history of a prior contact with unprocessed pork. The causative agent was isolated from blood cultures and aspirated synovial fluid. The patient's condition improved after treatment with penicillin, but he was found subsequently to have an abdominal aortic aneurysm, confirmed by computed tomography (CT) scan. The mycotic aneurysm was successfully repaired using an in situ graft reconstruction. Tissue samples analyzed using polymerase chain reaction identified S. suis serotype 2 as the causative organism. After completion of two weeks of parenteral antibiotics, an oral form of ciprofloxacin (0.25 g twice a day) was continued for one month. The patient was discharged from our institution after uncomplicated recovery. Clinical review, a CT scan, and inflammatory markers nine months after surgery revealed no evidence of infection.

CONCLUSION

This is the first report of mycotic aneurysm caused by S. suis, which may be an etiologic agent of mycotic aneurysms, especially when complicated by bacteremia in adults with a recent history of contact with pigs or unprocessed pork.

摘要

背景

猪链球菌是一种常见的猪感染病原体。人类感染通常与职业性接触猪和猪肉时意外接种通过皮肤损伤有关。该疾病可能表现为脑膜炎、菌血症,较少见的还有心内膜炎、关节炎或支气管肺炎。

方法

病例报告和文献复习。

结果

我们报告了一例由猪链球菌血清型 2 引起的菌血症和严重败血症,合并有既往接触未加工猪肉的 56 岁男性患者发生的化脓性关节炎。病原体从血液培养和抽吸的滑膜液中分离出来。患者在接受青霉素治疗后病情改善,但随后发现他患有腹主动脉瘤,经计算机断层扫描(CT)检查证实。使用原位移植物重建成功修复了真菌性动脉瘤。聚合酶链反应分析的组织样本鉴定出猪链球菌血清型 2 是致病病原体。在完成两周的静脉抗生素治疗后,继续口服环丙沙星(每天两次,每次 0.25 克)一个月。患者在无并发症恢复后从我院出院。术后九个月的临床复查、CT 扫描和炎症标志物均未显示感染证据。

结论

这是首例由猪链球菌引起的真菌性动脉瘤报告,可能是引起真菌性动脉瘤的病因之一,特别是在近期有接触猪或未加工猪肉史的成年患者中合并菌血症时。

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