First Department of Internal Medicine, University of Athens, Athens, Greece.
Clin Exp Rheumatol. 2009 Mar-Apr;27(2 Suppl 53):S85-7.
Behçet's disease (BD) is a multisystem inflammatory vasculitis of unknown etiology and pathogenesis. Coexistence of BD along with hematological malignancies is extremely rare. We describe a patient diagnosed with BD and chronic myelomonocytic leukaemia (CMML) with trisomy 8. This case suggests that trisomy 8 may be involved in the concurrent manifestation of myelodysplastic syndrome (MDS) and BD with gastrointestinal ulcers.
贝切特病(BD)是一种病因和发病机制不明的多系统炎症性血管炎。BD 与血液系统恶性肿瘤同时存在极为罕见。我们描述了一例同时诊断为 BD 和伴有 8 号三体的慢性粒单核细胞白血病(CMML)的患者。该病例提示 8 号三体可能与 MDS 和伴有胃肠道溃疡的 BD 的同时表现有关。