Sethi K D, Hess D C, Harp R J
Department of Neurology, Medical College of Georgia, Augusta 30912.
Mov Disord. 1990;5(4):319-21. doi: 10.1002/mds.870050411.
The prevalence of dystonia was studied in 125 veterans on chronic antipsychotic therapy using a detailed and systematic examination. Twenty-seven out of 125 had dystonic manifestations. The most common areas involved were hands and jaw. There was no relation between the presence or absence of dystonia, and duration of neuroleptic therapy. There was a tendency for tardive akathisia to occur more frequently in patients with dystonia than in those without it (Fisher's exact probability test, p = 0.0656). Tardive dystonia in its milder forms may be more common than currently believed.
通过详细而系统的检查,对125名接受慢性抗精神病药物治疗的退伍军人的肌张力障碍患病率进行了研究。125人中有27人有肌张力障碍表现。最常受累的部位是手部和下颌。肌张力障碍的有无与抗精神病药物治疗的持续时间之间没有关系。肌张力障碍患者比无肌张力障碍患者更易发生迟发性静坐不能(费舍尔精确概率检验,p = 0.0656)。轻度迟发性肌张力障碍可能比目前认为的更常见。