Saul'skaia N B
Neirofiziologiia. 1990;22(5):621-6.
The influence of n. accumbens on the striatal synaptic dopamine release was investigated in freely moving male Sprague-Dawley rats using in vivo intracranial dialysis followed by radioenzymatic analysis. It was shown that amphetamine or glutamic acid dialysis infusion in the n. accumbens resulted in a decrease in striatal extracellular dopamine level while simultaneous infusion of these drugs led to increase in striatal level of extracellular dopamine. It is suggested that there exist an influence of the n. accumbens on dopamine release in the striatum, the sign of this influence being mediated by dopamine-glutamic acid interaction in the n. accumbens.
利用体内颅内透析及放射酶分析法，在自由活动的雄性斯普拉格-道利大鼠中研究了伏隔核对纹状体突触多巴胺释放的影响。结果表明，向伏隔核内透析注入苯丙胺或谷氨酸会导致纹状体细胞外多巴胺水平降低，而同时注入这些药物则会导致纹状体细胞外多巴胺水平升高。提示伏隔核对纹状体中多巴胺释放存在影响，这种影响的信号是由伏隔核内多巴胺与谷氨酸的相互作用介导的。
