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Dietary glucosylceramide is absorbed into the lymph and increases levels of epidermal sphingolipids.

作者信息

Ishikawa Junko, Takada Shingo, Hashizume Kojiro, Takagi Yutaka, Hotta Mitsuyuki, Masukawa Yoshinori, Kitahara Takashi, Mizutani Yukiko, Igarashi Yasuyuki

出版信息

J Dermatol Sci. 2009 Dec;56(3):220-2. doi: 10.1016/j.jdermsci.2009.09.002. Epub 2009 Oct 3.

DOI:10.1016/j.jdermsci.2009.09.002
PMID:19800765
Abstract
摘要

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Dietary glucosylceramide is absorbed into the lymph and increases levels of epidermal sphingolipids.膳食中的葡萄糖神经酰胺被吸收进入淋巴,并增加表皮鞘脂的水平。
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An accumulation of glucosylceramide in the stratum corneum due to attenuated activity of beta-glucocerebrosidase is associated with the early phase of UVB-induced alteration in cutaneous barrier function.由于β-葡萄糖脑苷脂酶活性减弱导致角质层中葡糖神经酰胺蓄积,这与紫外线B诱导的皮肤屏障功能改变的早期阶段相关。
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Glucosylceramide accumulates preferentially in lamellar bodies in differentiated keratinocytes.葡萄糖神经酰胺优先在分化的角质形成细胞的板层小体中积累。
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