Gupta Himanshu, Sharma Aarti, Kumar Suresh, Roy Saroj K
Faculty of Pharmacy, Jamia Hamdard Hamdard University, New Delhi 110062, India.
Recent Pat Drug Deliv Formul. 2010 Jan;4(1):82-9. doi: 10.2174/187221110789957309.
Taste has an important role in the development of oral pharmaceuticals. With respect to patient acceptability and compliance, taste is one of the prime factors determining the market penetration and commercial success of oral formulations, especially in pediatric medicine. Taste assessment is one important quality-control parameter for evaluating taste-masked formulations. Hence, pharmaceutical industries invest time, money and resources into developing palatable and pleasant-tasting products. The primary method for the taste measurement of a drug substance or a formulation is by human sensory evaluation, in which tasting a sample is relayed to inspectors. However, this method is impractical for early stage drug development because the test in humans is expensive and the taste of a drug candidate may not be important to the final product. Therefore, taste-sensing analytical devices, which can detect tastes, have been replacing the taste panelists. In the present review we are presenting different aspect of electronic tongue. The review article also discussed some useful patents and instrument with respect to E-tongue.
味觉在口服药物的研发中起着重要作用。就患者的可接受性和依从性而言，味觉是决定口服制剂市场渗透率和商业成功的主要因素之一，尤其是在儿科医学领域。味觉评估是评价掩味制剂的一项重要质量控制参数。因此，制药行业投入时间、资金和资源来开发口感宜人、味道良好的产品。对原料药或制剂进行味觉测量的主要方法是通过人体感官评估，即将品尝样品的情况反馈给检验人员。然而，这种方法在药物研发早期并不实用，因为人体试验成本高昂，而且候选药物的味道对最终产品可能并不重要。因此，能够检测味道的味觉传感分析设备已逐渐取代了味觉评判员。在本综述中，我们介绍了电子舌的不同方面。这篇综述文章还讨论了一些与电子舌相关的有用专利和仪器。
