文献检索，用中文搜 PubMed

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Belan P V, Osipenko O N, Tepikin A V

A. A. Bogomoletz Institute of Physiology, Academy of Science of Ukranian S.S.R., Kiev.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1990;96(1):45-7. doi: 10.1016/0742-8413(90)90042-8.

Cytoplasmic Ca2+ concentration ICaIin and membrane potential of single Helix pomatia neurons was studied by Fura-2 fluorescence measurement and conventional current clamp methods. 2. Intracellular injection of inositol-1,4,5-trisphosphate (IP3) and nonhydrolysable GTP analogue (Gpp/NH/p) led to a rise of ICaIin; in contrast, GTP injection did not cause significant ICaIin changes. 3. We suggest that both IP3 and Gpp/NH/p directly activated Ca release from intracellular stores.

通过Fura-2荧光测量法和传统电流钳法研究了单枚苹果蜗牛神经元的细胞质Ca2+浓度（[Ca2+]i）和膜电位。2. 向细胞内注射肌醇-1,4,5-三磷酸（IP3）和不可水解的GTP类似物（Gpp/NH/p）会导致[Ca2+]i升高；相反，注射GTP不会引起[Ca2+]i的显著变化。3. 我们认为IP3和Gpp/NH/p均可直接激活细胞内钙库的钙释放。

Belan P V, Osipenko O N, Tepikin A V

A. A. Bogomoletz Institute of Physiology, Academy of Science of Ukranian S.S.R., Kiev.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1990;96(1):45-7. doi: 10.1016/0742-8413(90)90042-8.

Cytoplasmic Ca2+ concentration ICaIin and membrane potential of single Helix pomatia neurons was studied by Fura-2 fluorescence measurement and conventional current clamp methods. 2. Intracellular injection of inositol-1,4,5-trisphosphate (IP3) and nonhydrolysable GTP analogue (Gpp/NH/p) led to a rise of ICaIin; in contrast, GTP injection did not cause significant ICaIin changes. 3. We suggest that both IP3 and Gpp/NH/p directly activated Ca release from intracellular stores.

通过Fura-2荧光测量法和传统电流钳法研究了单枚苹果蜗牛神经元的细胞质Ca2+浓度（[Ca2+]i）和膜电位。2. 向细胞内注射肌醇-1,4,5-三磷酸（IP3）和不可水解的GTP类似物（Gpp/NH/p）会导致[Ca2+]i升高；相反，注射GTP不会引起[Ca2+]i的显著变化。3. 我们认为IP3和Gpp/NH/p均可直接激活细胞内钙库的钙释放。