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鸟苷三磷酸（GTP）增强肌醇三磷酸刺激的大鼠肝脏微粒体Ca2+释放。

GTP enhances inositol trisphosphate-stimulated Ca2+ release from rat liver microsomes.

作者信息

Dawson A P

出版信息

FEBS Lett. 1985 Jun 3;185(1):147-50. doi: 10.1016/0014-5793(85)80759-6.

DOI:10.1016/0014-5793(85)80759-6
PMID:3873359
Abstract

Low concentrations of GTP (10-50 microM) greatly enhance the inositol 1,4,5-trisphosphate stimulated Ca2+ release from rat liver microsomal vesicles. The effect of GTP depends on the presence of low concentrations of polyethylene glycol in the incubation medium. Guanylyl imidodiphosphate is ineffective at mimicking the GTP effect and inhibits the action of GTP added subsequently.

摘要

低浓度的鸟苷三磷酸（GTP，10 - 50微摩尔）能极大地增强肌醇1,4,5 - 三磷酸刺激大鼠肝微粒体囊泡释放钙离子的能力。GTP的这种作用取决于孵育介质中低浓度聚乙二醇的存在。鸟苷酰亚胺二磷酸无法模拟GTP的作用，且会抑制随后添加的GTP的作用。

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GTP enhances inositol trisphosphate-stimulated Ca2+ release from rat liver microsomes.鸟苷三磷酸（GTP）增强肌醇三磷酸刺激的大鼠肝脏微粒体Ca2+释放。
FEBS Lett. 1985 Jun 3;185(1):147-50. doi: 10.1016/0014-5793(85)80759-6.
2
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Biochem Biophys Res Commun. 1987 May 14;144(3):1313-6. doi: 10.1016/0006-291x(87)91453-7.

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