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肺嗜酸细胞瘤

Oncocytoma of the lung.

作者信息

Santos-Briz A, Terrón J, Sastre R, Romero L, Valle A

出版信息

Cancer. 1977 Sep;40(3):1330-6. doi: 10.1002/1097-0142(197709)40:3<1330::aid-cncr2820400350>3.0.co;2-k.

Abstract

A tumor diagnosed as an oncocytoma was removed from the lower right lung of a 22-year-old patient. Specimens from the formalin fixed tumor were studied by light microscopy and by electron microscopy. Large numbers of mitochondria were observed in all the tumor cells at the ultrastructural level despite many artefacts due to fixation. The presence of two tumor cell types "typical" oncocytes and "condensed" oncocytes were demonstrated by electron microscopy. This appears to be the second pulmonary oncocytoma in which mitochondrial hyperplaxia has been demonstrated. The tumor was similar to previously reported cases of salivary gland oncocytomas.

摘要

从一名22岁患者的右下肺切除了一个诊断为嗜酸细胞瘤的肿瘤。对福尔马林固定肿瘤的标本进行了光学显微镜和电子显微镜研究。尽管由于固定存在许多假象,但在超微结构水平上,所有肿瘤细胞中均观察到大量线粒体。电子显微镜证实存在两种肿瘤细胞类型,即“典型”嗜酸细胞和“浓缩”嗜酸细胞。这似乎是第二例已证实有线粒体增生的肺嗜酸细胞瘤。该肿瘤与先前报道的唾液腺嗜酸细胞瘤病例相似。

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