一例中性粒细胞增多与源自阴道直肠隔的复发性宫颈鳞状细胞癌相关的细胞因子产生。
A case of neutrophilia related to a cytokine-producing relapsed squamous cell carcinoma of the uterine cervix arising from the rectovaginal septum.
机构信息
Department of Laboratory Medicine, Chosun University School of Medicine, Gwangju, Korea.
出版信息
J Gynecol Oncol. 2009 Sep;20(3):187-91. doi: 10.3802/jgo.2009.20.3.187. Epub 2009 Sep 30.
Abstract
Paraneoplastic neutrophilia caused by a squamous cell carcinoma of the uterine cervix has been seen rarely. We report a case of relapsed squamous cell carcinoma of the uterine cervix with severe neutrophilia, rapid tumor growth and aggressive clinical course, possibly due to autocrine stimulation of cell growth by G-CSF and IL-6 without other possible causes of neutrophilia.
摘要
由宫颈鳞状细胞癌引起的副肿瘤性中性粒细胞增多症很少见。我们报告了一例宫颈鳞状细胞癌复发伴严重中性粒细胞增多症、肿瘤快速生长和侵袭性临床病程的病例，可能是由于 G-CSF 和 IL-6 的自分泌刺激细胞生长所致，而无其他可能引起中性粒细胞增多症的原因。
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