Office of Planning and Enterprise Development, Georgetown University Medical Center, 4000 Reservoir Road, NW, Washington DC 20057, USA.
Drug Discov Today. 2009 Nov;14(21-22):1006-10. doi: 10.1016/j.drudis.2009.09.007. Epub 2009 Oct 6.
Many parties contribute to discovery of new drugs - academic researchers, industry scientists, government agencies, and disease foundation helping to corral the resources necessary to sustain research efforts - but it has never been more apparent until now that these parties must work together to accomplish the shared goal of improving health. At a recent conference at the Georgetown University Medical Center, a group of prominent scientists from the academic, industry, government and disease advocacy communities came together to discuss new paths forward for stronger inter-institutional collaboration to establish a framework for translating new discoveries into drugs, improving proof of concept (PoC) studies, and reducing attrition at the clinical stage of drug development.
许多方面都为新药的发现做出了贡献——学术研究人员、行业科学家、政府机构和疾病基金会,他们共同努力,汇集必要的资源来支持研究工作——但直到现在,这些方面必须携手合作,才能实现改善健康这一共同目标。在乔治敦大学医学中心最近举行的一次会议上,来自学术界、产业界、政府和疾病倡导界的一组杰出科学家齐聚一堂,讨论了加强机构间合作的新途径,以建立一个将新发现转化为药物的框架,改进概念验证(PoC)研究,并减少药物开发临床阶段的淘汰率。