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在髋关节翻修术中用于打压植骨的加工骨与新鲜冷冻骨对比

Processed versus fresh frozen bone for impaction bone grafting in revision hip arthroplasty.

作者信息

Board Timothy N, Brunskill Susan, Doree Carolyn, Hyde Chris, Kay Peter R, Meek Rm Dominic, Webster Robert, Galea George

机构信息

The Centre for Hip Surgery, Wrightington Hospital, Appley Bridge, Wigan, Lancashire, UK, WN6 9EP.

出版信息

Cochrane Database Syst Rev. 2009 Oct 7;2009(4):CD006351. doi: 10.1002/14651858.CD006351.pub2.

DOI:10.1002/14651858.CD006351.pub2
PMID:19821362
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7386794/
Abstract

BACKGROUND

Impaction grafting is a technique to restore bone loss both in the femur and the acetabulum during revision hip arthroplasty surgery. Initially impaction grafting was undertaken using fresh frozen femoral head allografts that were milled to create morselized bone pieces that could be impacted to create a neo-cancellous bone bed prior to cementation of the new implant. Results of medium and long term outcome studies have shown variable results using this technique. Currently both processed and non-processed allograft bone are used and the purpose of this review was to analyse the evidence for both.

OBJECTIVES

To determine the clinical effectiveness of processed (freeze dried or irradiated) bone in comparison to fresh frozen (unprocessed) bone.

SEARCH STRATEGY

We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE (1985 to 2008), EMBASE (1985 to 2008), CINAHL(1985 to 2008) and the National Research Register. Additional sources were also searched. Handsearching of relevant journals and conference abstracts was also undertaken. Searches were complete to 31 August 2008.

SELECTION CRITERIA

Randomised controlled trials that compared different types of bone for impaction grafting.

DATA COLLECTION AND ANALYSIS

Three hundred and sixty references were identified from the searches. Following detailed eligibility screening, three hundred and fifty nine references did not meet the eligibility criteria. Further details are required about one trial in order to determine it's eligibility.

MAIN RESULTS

No trials were identified that met the criteria for inclusion in the review.

AUTHORS' CONCLUSIONS: Good quality randomised controlled trials are required in this area so that a surgeon's choice of bone graft can be informed by evidence rather than personal preference.

摘要

背景

打压植骨是一种在髋关节翻修手术中恢复股骨和髋臼骨量丢失的技术。最初,打压植骨使用的是新鲜冷冻的同种异体股骨头,将其研磨成碎骨块,在植入新假体前打压形成新的松质骨床。中长期结果研究显示,使用该技术的结果存在差异。目前,已处理和未处理的同种异体骨均有使用,本综述的目的是分析两者的证据。

目的

确定已处理(冻干或辐照)骨与新鲜冷冻(未处理)骨相比的临床有效性。

检索策略

我们检索了Cochrane对照试验中心注册库(CENTRAL)、MEDLINE(1985年至2008年)、EMBASE(1985年至2008年)、CINAHL(1985年至2008年)和国家研究注册库。还检索了其他来源。对相关期刊和会议摘要进行了手工检索。检索截至2008年8月31日。

选择标准

比较不同类型骨用于打压植骨的随机对照试验。

数据收集与分析

检索到360篇参考文献。经过详细的资格筛选,359篇参考文献不符合资格标准。为确定一项试验的资格,还需要更多详细信息。

主要结果

未发现符合纳入本综述标准的试验。

作者结论

该领域需要高质量的随机对照试验,以便外科医生在选择骨移植材料时能依据证据而非个人偏好。

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本文引用的文献

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Rinsing morcellised bone grafts with bisphosphonate solution prevents their resorption. A prospective randomised double-blinded study.用双膦酸盐溶液冲洗碎骨移植片可防止其吸收。一项前瞻性随机双盲研究。
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Femoral component revision with use of impaction bone-grafting and a cemented polished stem.采用打压植骨和骨水泥固定抛光柄进行股骨假体翻修术。
J Bone Joint Surg Am. 2005 Nov;87(11):2499-507. doi: 10.2106/JBJS.D.02547.
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Irradiated allograft bone for acetabular revision surgery. Results at a mean of five years.
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Acetabular reconstruction with impaction bone-grafting and a cemented cup in patients younger than fifty years old.50岁以下患者采用打压植骨和骨水泥杯进行髋臼重建。
J Bone Joint Surg Am. 2004 Nov;86(11):2385-92. doi: 10.2106/00004623-200411000-00004.
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Failure rates for 4762 revision total hip arthroplasties in the Norwegian Arthroplasty Register.挪威关节置换登记处4762例全髋关节翻修术的失败率。
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Acetabular revision with impacted morsellised cancellous bone grafting and a cemented cup. A 15- to 20-year follow-up.采用打压植骨松质骨移植和骨水泥臼杯进行髋臼翻修术。15至20年随访。
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Failure of an uncemented non-porous metal-backed prosthesis with augmentation using impacted allograft for acetabular revision 12- to 17-year results.
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