Department of Intensive Care Medicine, Tampere University Hospital, Tampere, Finland.
Scand J Trauma Resusc Emerg Med. 2009 Oct 12;17:53. doi: 10.1186/1757-7241-17-53.
Therapeutic hypothermia has been shown to improve survival and neurological outcome after prehospital cardiac arrest. Existing experimental and clinical evidence supports the notion that delayed cooling results in lesser benefit compared to early induction of mild hypothermia soon after return of spontaneous circulation. Therefore a practical approach would be to initiate cooling already in the prehospital setting. The purpose of this review was to evaluate current clinical studies on prehospital induction of mild hypothermia after cardiac arrest. Most reported studies present data on cooling rates, safety and feasibility of different methods, but are inconclusive as regarding to outcome effects.
治疗性低温治疗已被证明可改善院外心脏骤停后的存活率和神经功能结局。现有的实验和临床证据支持这样一种观点，即与自发循环恢复后早期诱导轻度低温相比，延迟降温的效果较差。因此，一种实用的方法是在院前环境中开始降温。本综述的目的是评估目前关于心脏骤停后院前诱导轻度低温的临床研究。大多数报告的研究都提供了关于冷却速度、不同方法的安全性和可行性的数据，但关于结局效果的结论尚无定论。
