Department of Epidemiology & Biostatistics, University of California, San Francisco 185 Berry Street, Lobby 3, Suite 6600, San Francisco, CA 94107, USA.
J Epidemiol Community Health. 2010 Sep;64(9):821-8. doi: 10.1136/jech.2009.086926. Epub 2009 Oct 12.
Despite different levels of economic development, Costa Rica and the USA have similar mortalities among adults. However, in the USA there are substantial differences in mortality by educational attainment, and in Costa Rica there are only minor differences. This contrast motivates an examination of behavioural and biological correlates underlying this difference.
The authors used data on adults aged 60 and above from the Costa Rican Longevity and Healthy Ageing Study (CRELES) (n=2827) and from the US National Health and Nutrition Examination Survey (NHANES) (n=5607) to analyse the cross-sectional association between educational level and the following risk factors for cardiovascular disease (CVD): ever smoked, current smoker, sedentary, high saturated fat, high carbohydrates, high calorie diet, obesity, severe obesity, large waist circumference, HDL cholesterol, LDL cholesterol, triglycerides, hemoglobin A1c, fasting glucose, C-reactive protein, systolic blood pressure and BMI.
There were significantly fewer hazardous levels of risk biomarkers at higher levels of education for more than half (10 out of 17) of the risk factors in the USA, but for less than a third of the outcomes in Costa Rica (five out of 17).
These results are consistent with the context-specific nature of educational differences in risk factors for CVD and with a non-uniform nature of association of CVD risk factors with education within countries. Our results also demonstrate that social equity in mortality is achieved without uniform equity in all risk factors.
尽管哥斯达黎加和美国的经济发展水平不同,但两国成年人的死亡率相似。然而,在美国,教育程度与死亡率之间存在显著差异,而在哥斯达黎加,这种差异则较小。这种对比促使人们研究导致这种差异的行为和生物学相关性。
作者使用了来自哥斯达黎加长寿与健康老龄化研究(CRELES)(n=2827)和美国国家健康与营养检查调查(NHANES)(n=5607)的 60 岁及以上成年人的数据,分析了教育水平与以下心血管疾病(CVD)风险因素之间的横断面关联:曾经吸烟、当前吸烟、久坐不动、高饱和脂肪、高碳水化合物、高卡路里饮食、肥胖、严重肥胖、腰围大、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、甘油三酯、血红蛋白 A1c、空腹血糖、C 反应蛋白、收缩压和 BMI。
在美国,超过一半(10 个中有 17 个)的风险因素中,教育程度越高,危险生物标志物的水平越低,但在哥斯达黎加,这种情况不到三分之一(17 个中有 5 个)。
这些结果与 CVD 风险因素中教育程度差异的特定情境性质以及 CVD 风险因素与国内教育程度之间的非一致性关联相一致。我们的结果还表明,在死亡率方面实现社会公平并不意味着所有风险因素都实现了公平。