Kumar Rajesh S, Tantisevi Visanee, Wong Melissa H, Laohapojanart Kobkuea, Chansanti Orathai, Quek Desmond T, Koh Victor T, MohanRam Lakshmana S, Lee Kelvin Y, Rojanapongpun Prin, Aung Tin
Singapore National Eye Centre and Singapore Eye Research Institute, Singapore.
Arch Ophthalmol. 2009 Oct;127(10):1269-72. doi: 10.1001/archophthalmol.2009.241.
To determine the prevalence of plateau iris in Asian eyes with primary angle closure glaucoma (PACG) using ultrasound biomicroscopy (UBM).
In this cross-sectional observational study, subjects older than 40 years with PACG who had a patent laser peripheral iridotomy underwent UBM in 1 eye. Ultrasound biomicroscopy images were qualitatively analyzed using standardized criteria. Plateau iris in a quadrant was defined by anteriorly directed ciliary body, absent ciliary sulcus, steep iris root from its point of insertion followed by a downward angulation, flat iris plane, and irido-angle contact. At least 2 quadrants had to fulfill these UBM criteria for an eye to be classified as having plateau iris.
One hundred eleven subjects (70 from Singapore, 41 from Thailand) with PACG were recruited. The mean (SD) age was 65.6 (8.1) years, and 63.9% were female. Based on standardized UBM criteria, plateau iris was found in 36 of 111 eyes (32.4%; 95% confidence interval, 24.4%-41.6%). In these 36 eyes, quadrant-wise analysis showed 66.7% had plateau iris in 2 quadrants; 22.2%, in 3 quadrants; and 11.1%, in all quadrants.
About 30% of PACG eyes with a patent laser peripheral iridotomy were found to have plateau iris on UBM, highlighting the importance of non-pupil block mechanisms in Asian individuals.
使用超声生物显微镜（UBM）确定亚洲原发性闭角型青光眼（PACG）患者中高原虹膜的患病率。
在这项横断面观察性研究中，年龄超过40岁且接受过激光周边虹膜切开术的PACG患者单眼接受UBM检查。使用标准化标准对超声生物显微镜图像进行定性分析。象限内的高原虹膜定义为睫状体向前、睫状沟缺失、虹膜根部自插入点起陡峭并伴有向下成角、虹膜平面平坦以及虹膜与房角接触。一只眼睛至少有2个象限符合这些UBM标准才能被分类为患有高原虹膜。
招募了111名PACG患者（70名来自新加坡，41名来自泰国）。平均（标准差）年龄为65.6（8.1）岁，女性占63.9%。根据标准化UBM标准，111只眼中有36只（32.4%；95%置信区间，24.4%-41.6%）发现有高原虹膜。在这36只眼中，按象限分析显示，66.7%的眼睛在2个象限有高原虹膜；22.2%在3个象限；11.1%在所有象限。
在接受过激光周边虹膜切开术的PACG眼中，约30%在UBM检查中发现有高原虹膜，这突出了亚洲个体中非瞳孔阻滞机制的重要性。
