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原发性闭角型青光眼中高原虹膜的患病率：一项基于埃及医院的超声生物显微镜研究

Prevalence of Plateau Iris in Primary Angle Closure Glaucoma: An Egyptian Hospital Based Ultrasound Biomicroscopy Study.

作者信息

Hamad Amira E, Elmaria Ahmed F, Hussein Tarek R, Shalaby Said M

机构信息

Tanta Ophthalmology Hospital, Ministry of Health, Tanta, Elgharbia Province, Egypt.

Department of Ophthalmology, Tanta University, Tanta, Elgharbia Province, Egypt.

出版信息

Clin Ophthalmol. 2022 Feb 25;16:541-550. doi: 10.2147/OPTH.S356106. eCollection 2022.

DOI:10.2147/OPTH.S356106
PMID:35241909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8887914/
Abstract

PURPOSE

To determine the distribution and the anatomical characteristics of plateau iris (PI) in primary angle closure glaucoma (PACG) using ultrasound biomicroscopy (UBM).

METHODS

Fifty UBM images of PACG cases were studied over one year by retrospective analysis. The data from UBM images including angle opening distance at 500 and 750 μm (AOD500 and AOD750), trabecular-iris angle (TIA), angle recess area at 750 μm (ARA750), maximum ciliary body thickness (CBTmax), anterior placement of ciliary processes (APCP), central anterior chamber depth (CACD), axial lens thickness (ALT), and ciliary sulcus status were analyzed and compared between the PI and non-PI cases.

RESULTS

Eighteen cases had PI (36%). The mean AOD500, AOD750, and TIA were significantly smaller in PI than in non-PI eyes ( = 0.01; = 0.046; and = 0.026). Values of the ARA750 and CBTmax were not significantly different between the two groups ( = 0.208 and = 0.368). CACD was deeper in the PI group ( = 0.011). ALT was higher in the non-PI group ( = 0.001). The mean APCP of the PI group was more than those of the non-PI group ( < 0.001). The number of cases with obliterated ciliary sulcus in more than two quadrants was significantly more in the PI group ( < 0.001).

CONCLUSION

Around one-third of PACG eyes were found to have PI on UBM imaging. The number of obliterated ciliary sulcus and APCP were important UBM parameters that help in PI diagnosis.

摘要

目的

使用超声生物显微镜（UBM）确定原发性闭角型青光眼（PACG）中高原虹膜（PI）的分布及解剖特征。

方法

通过回顾性分析，对一年内50例PACG病例的UBM图像进行研究。分析并比较PI组和非PI组UBM图像数据，包括500和750μm处的房角开放距离（AOD500和AOD750）、小梁-虹膜夹角（TIA）、750μm处的房角隐窝面积（ARA750）、睫状体最大厚度（CBTmax）、睫状突前位（APCP）、中央前房深度（CACD）、晶状体轴厚（ALT）以及睫状沟状态。

结果

18例有PI（36%）。PI组的平均AOD500、AOD750和TIA显著小于非PI组（P = 0.01；P = 0.046；P = 0.026）。两组间ARA750和CBTmax值无显著差异（P = 0.208和P = 0.368）。PI组CACD更深（P = 0.011）。非PI组ALT更高（P = 0.001）。PI组的平均APCP大于非PI组（P < 0.001）。PI组中超过两个象限睫状沟闭塞的病例数显著更多（P < 0.001）。

结论

在UBM成像中，约三分之一的PACG眼有PI。睫状沟闭塞数量和APCP是有助于PI诊断的重要UBM参数。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdc/8887914/e45e1813e3a9/OPTH-16-541-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdc/8887914/e995978f7ada/OPTH-16-541-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdc/8887914/7f449357d809/OPTH-16-541-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdc/8887914/1798154b0ab0/OPTH-16-541-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdc/8887914/3328ebf30974/OPTH-16-541-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdc/8887914/e45e1813e3a9/OPTH-16-541-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdc/8887914/e995978f7ada/OPTH-16-541-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdc/8887914/7f449357d809/OPTH-16-541-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdc/8887914/1798154b0ab0/OPTH-16-541-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdc/8887914/3328ebf30974/OPTH-16-541-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdc/8887914/e45e1813e3a9/OPTH-16-541-g0005.jpg

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