CBS-KNAW Fungal Biodiversity Centre, Yeast and Basidiomycete Research, Uppsalalaan 8, Utrecht, The Netherlands.
Med Mycol. 2010 May;48(3):528-31. doi: 10.3109/13693780903300319.
An ongoing outbreak of Cryptococcus gattii-caused infections, which emerged on Vancouver Island and the Pacific Northwest, has affected more than 200 of the islands' residents, of whom eight died. While C. gattii infections are rarely described in travelers, we report a case of cryptococcosis caused by C. gattii in a patient treated with high dose corticosteroids for systemic lupus erythematosus induced autoimmune hemolytic anemia. She acquired the disease during a visit to Vancouver Island one year before the onset of the symptoms. This indicates that C. gattii may cause a dormant infection that can be activated during treatment with corticosteroids.
温哥华岛和西北太平洋地区爆发了隐球菌性感染疫情,目前已有 200 多名岛民受到影响,其中 8 人死亡。虽然旅行者中很少有隐球菌感染的描述,但我们报告了一例系统性红斑狼疮诱导自身免疫性溶血性贫血患者因接受大剂量皮质类固醇治疗而引起的隐球菌病。她在症状出现前一年到温哥华岛旅行时感染了该疾病。这表明隐球菌可能引起潜伏感染,在接受皮质类固醇治疗时可能会被激活。