Montoro J B, Galard R, Catalan R, Martinez J, Salvador P, Sabin P
Hospital Pharmacy Service, Hospital General Vall d'Hebron, Barcelona, Spain.
Pharm Weekbl Sci. 1990 Dec 14;12(6):240-2. doi: 10.1007/BF01967824.
The stability of somatostatin, added to a total parenteral nutrition formula, in glass containers and in plastic ethylene vinyl acetate containers was investigated. The somatostatin concentration decreased immediately from 3 micrograms/ml to 0.3-0.6 micrograms/ml after addition to the emulsion. In spite of this rapid decrease, somatostatin concentrations remained stable with values of 0.4-0.7 micrograms/ml during the follow-up period (24 h). These findings could be explained assuming adsorption to the surface of the container.
研究了添加到全胃肠外营养配方中的生长抑素在玻璃容器和乙烯-醋酸乙烯共聚物塑料容器中的稳定性。生长抑素添加到乳剂中后，其浓度立即从3微克/毫升降至0.3 - 0.6微克/毫升。尽管有这种快速下降，但在随访期（24小时）内生长抑素浓度保持稳定，值为0.4 - 0.7微克/毫升。这些发现可以通过假设其吸附到容器表面来解释。
