Shale Matt, Ghosh Subrata
Imperial College London, Hammersmith Hospital, London, United Kingdom.
Can J Gastroenterol. 2009 Oct;23(10):674-6. doi: 10.1155/2009/514618.
Psoriasis or psoriasiform skin lesions, as an adverse effect of treatment with antitumor necrosis factor antibody therapy, have been described relatively recently. Patients with these lesions have no personal or family history of psoriasis. In a small number of cases, an association with Chlamydia has been suggested. The skin lesions may disappear on discontinuation of therapy or, in the majority of cases, even if antitumor necrosis factor antibody therapy is continued. Therefore, withdrawal of therapy is generally not required for this adverse effect but referral to a dermatologist may be desirable for confirmation of diagnosis and treatment.
银屑病或银屑病样皮肤病变作为抗肿瘤坏死因子抗体治疗的一种不良反应，是最近才被描述的。患有这些病变的患者没有银屑病的个人或家族病史。在少数病例中，有人提出与衣原体有关。皮肤病变可能在治疗中断后消失，或者在大多数情况下，即使继续使用抗肿瘤坏死因子抗体治疗也会消失。因此，一般不需要因这种不良反应而停药，但为了确诊和治疗，最好转诊给皮肤科医生。
