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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Tan N H, Saifuddin M N

Department of Biochemistry, University of Malaya, Kuala Lumpur.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1990;97(2):293-6. doi: 10.1016/0742-8413(90)90144-x.

The edema-inducing activity of 24 venoms from snakes of the subfamilies of Elapinae, Hydrophiini, Crotalinae and Viperinae was determined. 2. All snake venoms tested are very potent edema inducers. The minimum edema doses of the venoms ranged from 0.16 to 3.41 micrograms per mouse paw. 3. The venoms induced a rapid onset edema which peaked within 1 h of injection and declined thereafter; at low dose, however, some venoms induced a rapid onset edema that sustained over a longer duration.

测定了眼镜蛇亚科、海蛇亚科、蝰蛇亚科和蝮蛇亚科24种蛇毒的致水肿活性。2. 所有受试蛇毒都是非常有效的水肿诱导剂。这些蛇毒的最小致水肿剂量为每只小鼠爪0.16至3.41微克。3. 蛇毒诱导的水肿起效迅速，在注射后1小时内达到峰值，随后下降；然而，在低剂量时，一些蛇毒诱导的水肿起效迅速且持续时间更长。

Tan N H, Saifuddin M N

Department of Biochemistry, University of Malaya, Kuala Lumpur.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1990;97(2):293-6. doi: 10.1016/0742-8413(90)90144-x.

The edema-inducing activity of 24 venoms from snakes of the subfamilies of Elapinae, Hydrophiini, Crotalinae and Viperinae was determined. 2. All snake venoms tested are very potent edema inducers. The minimum edema doses of the venoms ranged from 0.16 to 3.41 micrograms per mouse paw. 3. The venoms induced a rapid onset edema which peaked within 1 h of injection and declined thereafter; at low dose, however, some venoms induced a rapid onset edema that sustained over a longer duration.

测定了眼镜蛇亚科、海蛇亚科、蝰蛇亚科和蝮蛇亚科24种蛇毒的致水肿活性。2. 所有受试蛇毒都是非常有效的水肿诱导剂。这些蛇毒的最小致水肿剂量为每只小鼠爪0.16至3.41微克。3. 蛇毒诱导的水肿起效迅速，在注射后1小时内达到峰值，随后下降；然而，在低剂量时，一些蛇毒诱导的水肿起效迅速且持续时间更长。