Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway.
Dement Geriatr Cogn Disord. 2009;28(4):307-13. doi: 10.1159/000247586. Epub 2009 Oct 14.
BACKGROUND/AIMS: Orthostatic hypotension (OH) and QTc prolongation have potentially important prognostic and therapeutic consequences but have rarely been studied in patients with mild dementia.
Patients with mild dementia were diagnosed according to consensus criteria after comprehensive standardized assessment. OH and QTc were assessed using standardized criteria.
OH was significantly more common in the dementia than in the control group, and systolic drop was higher in those with dementia with Lewy bodies. There were no significant differences in QTc values between dementia and control subjects.
OH occurs even in patients with mild dementia, in particular in dementia with Lewy bodies. QTc was not prolonged in patients with mild dementia compared with normal controls.
背景/目的：直立性低血压（OH）和 QTc 延长具有重要的预后和治疗意义，但在轻度痴呆患者中很少研究。
根据综合标准化评估后的共识标准，对轻度痴呆患者进行诊断。使用标准化标准评估 OH 和 QTc。
OH 在痴呆组中明显比对照组更常见，而在路易体痴呆患者中收缩压下降更高。痴呆组和对照组的 QTc 值无显著差异。
即使是轻度痴呆患者也会发生 OH，尤其是路易体痴呆患者。与正常对照组相比，轻度痴呆患者的 QTc 并未延长。
