Oshita Hideto, Matsumoto Hiromi, Hoshino Teppei, Omori Keitaro, Okamoto Naoki, Awaya Yukikazu
Department of Respiratory Medicine, Chugoku Rosai General Hospital, 1-5-1, Hiro-tagaya, Kure-shi, Hiroshima 737-0193, Japan.
Cases J. 2009 Jun 26;2:6323. doi: 10.4076/1757-1626-2-6323.
Accurate evaluation of disease status is very important in treatment of Wegener's granulomatosis
A 73-year-old Japanese man presented with chronic sinusitis and otitis media. He was admitted to our hospital because of bilateral lung nodules. Cytoplasmic antineutrophil cytoplasmic antibody was negative but his rheumatoid factor was high. He was diagnosed with limited Wegener's granulomatosis and received remission induction therapy. His serum rheumatoid factor level correlated with the Wegener's granulomatosis state when he experienced a severe infection and recurrence due to Wegener's granulomatosis.
We describe a case of Wegener's granulomatosis in which rheumatoid factor was helpful for evaluating the therapeutic effect.
在韦格纳肉芽肿的治疗中,准确评估疾病状态非常重要。
一名73岁的日本男性,患有慢性鼻窦炎和中耳炎。因双侧肺结节入住我院。胞浆抗中性粒细胞胞浆抗体阴性,但类风湿因子水平较高。他被诊断为局限性韦格纳肉芽肿,并接受了诱导缓解治疗。在他因韦格纳肉芽肿发生严重感染和复发时,其血清类风湿因子水平与韦格纳肉芽肿状态相关。
我们报告了一例类风湿因子有助于评估治疗效果的韦格纳肉芽肿病例。