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右足第2趾近节趾骨2级经关节软骨肉瘤导致其骨折并伴有中节趾骨破坏:1例报告及文献复习

Trans-articular chondrosarcoma grade 2 of proximal phalanx resulting in its fracture along with destruction of middle phalanx of 2 toe right foot: a case report and review of the literature.

作者信息

Bashir Sheikh Irfan, Gupta Rajesh, Khan Haris Nazir, Ahmed Rayees, Mohd Ashraf, Salaria Abdul Q

机构信息

Postgraduate Boys Hostel Room No 112 B, Government Medical College Bakshi Nager, Jammu, Jammu and Kashmir India.

出版信息

Cases J. 2009 Jul 6;2:7488. doi: 10.4076/1757-1626-2-7488.

Abstract

Foot is an unusual site for chondrosarcoma and involvement of phalanges is extremely rare. We report a case of grade 2 chondrosarcoma of proximal phalanx resulting in its fracture along with transarticular extension to the middle phalanx of the 2(nd) toe of right foot in a 62 year old female. The patient presented with 1 and (1/2) year history of pain and swelling in right 2(nd) toe. X-ray showed presence of expanding lytic lesion with amorphous calcification along with fracture proximal phalanx. Fine needle aspiration cytology showed some pleomorphs, osteoclasts and some giant cells. We went for amputation of toe without a biopsy. Histopathological examination of specimen showed multiple pleomorphic cells, nuclear atypia, hyperchromasia with some giant cells (grade 2 chondrosarcoma).

摘要

足部是软骨肉瘤的罕见发病部位,累及趾骨极为罕见。我们报告一例62岁女性右足第2趾近节趾骨2级软骨肉瘤病例,该肿瘤导致近节趾骨骨折,并经关节延伸至中节趾骨。患者有右第2趾疼痛和肿胀1年半的病史。X线显示有膨胀性溶骨性病变伴无定形钙化,以及近节趾骨骨折。细针穿刺细胞学检查显示有一些多形性细胞、破骨细胞和一些巨细胞。我们未进行活检就实施了截趾手术。标本的组织病理学检查显示有多个多形性细胞、核异型性、核深染以及一些巨细胞(2级软骨肉瘤)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3945/2740285/60011c3a4a48/1757-1626-0002-0000007488-001.jpg

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