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肝内脾组织异位作为丙型肝炎和肝硬化患者局灶性肝病变的意外病因:一例报告

Intra-hepatic splenosis as an unexpected cause of a focal liver lesion in a patient with hepatitis C and liver cirrhosis: a case report.

作者信息

Menth Marianne, Herrmann Karin, Haug Alexander, Raziorrouh Bijan, Zachoval Reinhart, Jung Christina-Maria, Otto Carsten

机构信息

Medical Department 2, University of Munich - GrosshadernMarchioninistrasse 15, D-81377 MunichGermany.

Institute of Clinical Radiology, University of Munich - GrosshadernMarchioninistrasse 15, D-81377 MunichGermany.

出版信息

Cases J. 2009 Aug 19;2:8335. doi: 10.4076/1757-1626-2-8335.

Abstract

INTRODUCTION

Splenosis is the heterotopic autotransplantation of splenic tissue, mostly found after splenic trauma or surgery in the abdominal, pelvic or thoracic cavity. Here we report a patient with a history of splenectomy after polytrauma with chronic hepatitis C and liver cirrhosis presenting with an hepatic mass of unknown origin.

CASE PRESENTATION

The lesion could not be exactly classified by ultrasound, computed tomography, angiography and biopsy, classical features of malignancy were not fulfilled, and on the other hand a neoplastic process could neither be excluded. After revision of a MRI performed in our centre it appeared that the liver mass contrasted in the same way as the remaining accessory spleens in the left upper quadrant. A selective Tc-99m-labelled heat-denatured autologous red blood cells scintigraphy of the spleen was performed and showed both the accessory spleens in the left upper quadrant and spleen-typical tissue in projection to the left liver lobe and confirmed the diagnosis of splenosis.

CONCLUSION

Although intrahepatic splenosis represents an extremely rare condition, this diagnosis should always be taken into consideration in patients with history of abdominal trauma with splenic involvement presenting with an indeterminate focal liver lesion. The diagnosis of splenosis may then be reliably confirmed by Tc-99m-DRBC scintigraphy.

摘要

引言

脾组织异位自体移植是脾组织的异位移植,多见于脾外伤或腹腔、盆腔或胸腔手术后。本文报告1例多发伤后脾切除患者,合并慢性丙型肝炎和肝硬化,出现不明原因的肝脏肿块。

病例介绍

通过超声、计算机断层扫描、血管造影和活检无法对病变进行准确分类,不符合恶性肿瘤的典型特征,但另一方面也不能排除肿瘤性病变。在对我院进行的磁共振成像检查结果进行复查后发现,肝脏肿块的造影表现与左上腹其余副脾相同。进行了选择性锝-99m标记热变性自体红细胞脾闪烁显像,显示左上腹的副脾以及左肝叶投影处的典型脾组织,确诊为脾组织异位。

结论

尽管肝内脾组织异位极为罕见,但对于有腹部外伤史且脾脏受累、出现不明局灶性肝病变的患者,应始终考虑这一诊断。锝-99m标记变性红细胞闪烁显像可可靠地确诊脾组织异位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0b5/2740154/0c7cbca90541/1757-1626-0002-0000008335-001.jpg

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