Snieders Marieke N, van Kemenade Folkert J, van Royen Barend J
J Med Case Rep. 2009 Jun 24;3:7227. doi: 10.4076/1752-1947-3-7227.
We report the case of a 25-year-old Caucasian woman with symptomatic monostotic fibrous dysplasia of the fourth lumbar vertebral body. The patient suffered from a five-week history of progressive low back pain, radiating continuously to the left leg. Her medical history and physical and neurological examination did not demonstrate any significant abnormalities. Radiographs, computed tomography and magnetic resonance imaging revealed an osteolytic expansive lesion with a cystic component of the fourth lumbar vertebral body. Percutaneous transpedicular biopsy showed histological characteristics of fibrous dysplasia superimposed by the formation of aneurysmal bone cyst components. The patient was treated by subtotal vertebrectomy of the L4 vertebral body with anterior reconstruction and her postoperative course was uncomplicated. To our knowledge, this is the first reported case of a monostotic fibrous dysplasia with superimposed secondary aneurysmal bone cysts of a lumbar vertebral body.
我们报告了一例25岁的白种女性病例,其第四腰椎椎体患有症状性单骨纤维发育不良。患者有长达五周的进行性下背痛病史,疼痛持续放射至左腿。她的病史、体格检查和神经学检查均未显示任何明显异常。X线片、计算机断层扫描和磁共振成像显示第四腰椎椎体有一个溶骨性膨胀性病变,伴有囊性成分。经皮椎弓根活检显示纤维发育不良的组织学特征,并伴有动脉瘤样骨囊肿成分的形成。患者接受了L4椎体次全切除及前路重建治疗,术后恢复过程顺利。据我们所知,这是首例报道的腰椎椎体单骨纤维发育不良合并继发性动脉瘤样骨囊肿的病例。