Ahmad Zuber, Zubair Ishma
Department of Tuberculosis and Respiratory Diseases , J. N. Medical College AMU , Aligarh, Uttar Pradesh , India.
Oxf Med Case Reports. 2015 Feb 26;2015(2):196-9. doi: 10.1093/omcr/omv006. eCollection 2015 Feb.
Fibrous dysplasia (FD) is a benign skeletal disorder that can affect one bone (monostotic form) or multiple bones (polyostotic form). It is a non-inherited bone disease, in which abnormal differentiation of osteoblasts leads to replacement of normal marrow and cancellous bone by immature bone with fibrous stroma. It is often asymptomatic and incidentally detected on radiographs. We report this rare disorder in a 22-year-old lady who presented to us with cough and breathlessness. Her chest radiograph showed a cystic mass extending into the chest wall. On computed tomography scan, mass turned out to be FD of the second rib. Histopathology of the lesion confirmed the diagnosis.
骨纤维异常增殖症(FD)是一种良性骨骼疾病,可累及一块骨骼(单骨型)或多块骨骼(多骨型)。它是一种非遗传性骨病,其中成骨细胞的异常分化导致正常骨髓和松质骨被带有纤维基质的未成熟骨替代。该病通常无症状,常在X线片检查时偶然发现。我们报告了一位22岁女性患者的这一罕见疾病,她因咳嗽和呼吸急促前来就诊。她的胸部X线片显示一个囊性肿物延伸至胸壁。在计算机断层扫描中,肿物被证实为第二肋骨的骨纤维异常增殖症。病变的组织病理学检查确诊了该诊断。