Yucel Mehmet, Kabay Sahin, Saracoglu Ugur, Yalcinkaya Soner, Hatipoglu Namik Kemal, Aras Erol
J Med Case Rep. 2009 May 29;3:7266. doi: 10.1186/1752-1947-3-7266.
Burned-out testicular tumour is a very rare clinical entity. There is no clinical finding in the testicle, because it regresses spontaneously with no treatment, and generally presents with metastases. Abdominal masses in young male patients may sometimes be caused by a metastatic burned-out testicular tumour. We report a patient with a burned-out testicular tumour that metastasized to retroperitoneal lymph nodes.
A 28-year-old man complained of an abdominal mass and continuously increasing pain over the previous 2 months. A midabdominal mass, atrophy and minimal induration in the right testis were revealed on physical examination. Ultrasound findings revealed focally increased echogenicity, which is typical of burned-out tumours. Inguinal orchiectomy was performed, and the histological examination of the biopsy specimen revealed a large area of hyalinization, tubular hyalinization, interstitial fibrosis and focal Leydig cell hyperplasia, with no abnormal pathological findings in the epididymis and spermatic cord. The final pathological diagnosis was concluded as "burned-out" testicular tumour. Surgical treatment was followed by appropriate chemotherapy and in the follow-up, the abdominal mass was observed to regress. The patient is currently free of disease 5 years after diagnosis.
For the detection of intratesticular lesions, especially in patients with extragonadal metastatic involvement and normal palpation findings for the testis, scrotal sonography is very important. A burned-out testicular tumour should be considered and testis biopsies should be performed if there is any risk factor of malignancy.
消退性睾丸肿瘤是一种非常罕见的临床实体。睾丸内无临床发现,因为它未经治疗即可自发消退,且通常表现为转移。年轻男性患者的腹部肿块有时可能由转移性消退性睾丸肿瘤引起。我们报告一例消退性睾丸肿瘤转移至腹膜后淋巴结的患者。
一名28岁男性主诉在过去2个月中出现腹部肿块且疼痛持续加剧。体格检查发现中腹部有肿块,右侧睾丸萎缩且有轻度硬结。超声检查结果显示局部回声增强,这是消退性肿瘤的典型表现。进行了腹股沟睾丸切除术,活检标本的组织学检查显示大面积玻璃样变、管状玻璃样变、间质纤维化和局灶性Leydig细胞增生,附睾和精索未发现异常病理表现。最终病理诊断为“消退性”睾丸肿瘤。手术治疗后进行了适当的化疗,在随访中观察到腹部肿块消退。该患者在诊断后5年目前无疾病。
对于睾丸内病变的检测,尤其是对于有性腺外转移累及且睾丸触诊结果正常的患者,阴囊超声检查非常重要。如果存在任何恶性肿瘤风险因素,应考虑消退性睾丸肿瘤并进行睾丸活检。