• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

睾丸肿瘤消退后转移至腹膜后淋巴结:一例报告。

Burned-out testis tumour that metastasized to retroperitoneal lymph nodes: a case report.

作者信息

Yucel Mehmet, Kabay Sahin, Saracoglu Ugur, Yalcinkaya Soner, Hatipoglu Namik Kemal, Aras Erol

出版信息

J Med Case Rep. 2009 May 29;3:7266. doi: 10.1186/1752-1947-3-7266.

DOI:10.1186/1752-1947-3-7266
PMID:19830158
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2726527/
Abstract

INTRODUCTION

Burned-out testicular tumour is a very rare clinical entity. There is no clinical finding in the testicle, because it regresses spontaneously with no treatment, and generally presents with metastases. Abdominal masses in young male patients may sometimes be caused by a metastatic burned-out testicular tumour. We report a patient with a burned-out testicular tumour that metastasized to retroperitoneal lymph nodes.

CASE PRESENTATION

A 28-year-old man complained of an abdominal mass and continuously increasing pain over the previous 2 months. A midabdominal mass, atrophy and minimal induration in the right testis were revealed on physical examination. Ultrasound findings revealed focally increased echogenicity, which is typical of burned-out tumours. Inguinal orchiectomy was performed, and the histological examination of the biopsy specimen revealed a large area of hyalinization, tubular hyalinization, interstitial fibrosis and focal Leydig cell hyperplasia, with no abnormal pathological findings in the epididymis and spermatic cord. The final pathological diagnosis was concluded as "burned-out" testicular tumour. Surgical treatment was followed by appropriate chemotherapy and in the follow-up, the abdominal mass was observed to regress. The patient is currently free of disease 5 years after diagnosis.

CONCLUSION

For the detection of intratesticular lesions, especially in patients with extragonadal metastatic involvement and normal palpation findings for the testis, scrotal sonography is very important. A burned-out testicular tumour should be considered and testis biopsies should be performed if there is any risk factor of malignancy.

摘要

引言

消退性睾丸肿瘤是一种非常罕见的临床实体。睾丸内无临床发现,因为它未经治疗即可自发消退,且通常表现为转移。年轻男性患者的腹部肿块有时可能由转移性消退性睾丸肿瘤引起。我们报告一例消退性睾丸肿瘤转移至腹膜后淋巴结的患者。

病例介绍

一名28岁男性主诉在过去2个月中出现腹部肿块且疼痛持续加剧。体格检查发现中腹部有肿块,右侧睾丸萎缩且有轻度硬结。超声检查结果显示局部回声增强,这是消退性肿瘤的典型表现。进行了腹股沟睾丸切除术,活检标本的组织学检查显示大面积玻璃样变、管状玻璃样变、间质纤维化和局灶性Leydig细胞增生,附睾和精索未发现异常病理表现。最终病理诊断为“消退性”睾丸肿瘤。手术治疗后进行了适当的化疗,在随访中观察到腹部肿块消退。该患者在诊断后5年目前无疾病。

结论

对于睾丸内病变的检测,尤其是对于有性腺外转移累及且睾丸触诊结果正常的患者,阴囊超声检查非常重要。如果存在任何恶性肿瘤风险因素,应考虑消退性睾丸肿瘤并进行睾丸活检。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b85c/2726527/fe9002ed1bba/1752-1947-0003-0000007266-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b85c/2726527/7d365765837b/1752-1947-0003-0000007266-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b85c/2726527/c765b506d5b3/1752-1947-0003-0000007266-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b85c/2726527/fe9002ed1bba/1752-1947-0003-0000007266-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b85c/2726527/7d365765837b/1752-1947-0003-0000007266-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b85c/2726527/c765b506d5b3/1752-1947-0003-0000007266-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b85c/2726527/fe9002ed1bba/1752-1947-0003-0000007266-3.jpg

相似文献

1
Burned-out testis tumour that metastasized to retroperitoneal lymph nodes: a case report.睾丸肿瘤消退后转移至腹膜后淋巴结:一例报告。
J Med Case Rep. 2009 May 29;3:7266. doi: 10.1186/1752-1947-3-7266.
2
["Burned out" testicular tumor: a rare form of germ cell neoplasias].“耗竭型”睾丸肿瘤:生殖细胞肿瘤的一种罕见形式
Schweiz Med Wochenschr. 1999 Feb 13;129(6):235-40.
3
[Burned-out testicular germ cell tumors: a clinicopathological analysis of three cases].[消退型睾丸生殖细胞肿瘤:3例临床病理分析]
Zhonghua Bing Li Xue Za Zhi. 2023 Apr 8;52(4):347-352. doi: 10.3760/cma.j.cn112151-20221124-00990.
4
Burned-Out Testicular Tumor Presenting as a Retroperitoneal Mass: A Case Report.以腹膜后肿块形式出现的坏死性睾丸肿瘤:一例报告。
Cureus. 2022 Jan 25;14(1):e21603. doi: 10.7759/cureus.21603. eCollection 2022 Jan.
5
Ultrasound and Magnetic Resonance Imaging of Burned-Out Testicular Tumours: The Diagnostic Keys Based on 48 Cases.萎缩性睾丸肿瘤的超声与磁共振成像:基于48例病例的诊断要点
Cancers (Basel). 2022 Aug 19;14(16):4013. doi: 10.3390/cancers14164013.
6
Burned-out metastatic testicular tumor: Choriocarcinoma.消退性转移性睾丸肿瘤:绒毛膜癌。
Int J Health Sci (Qassim). 2017 Apr-Jun;11(2):81-82.
7
'Burned-out' syndrome of testicular teratoma: A case report.睾丸畸胎瘤“消退”综合征:一例报告
Mol Clin Oncol. 2021 Dec;15(6):262. doi: 10.3892/mco.2021.2424. Epub 2021 Oct 22.
8
[Extragonadal germ cell tumor with "burned-out" phenomenon in the testis].睾丸存在“消退”现象的性腺外生殖细胞肿瘤
Actas Urol Esp. 1999 Nov-Dec;23(10):880-4. doi: 10.1016/s0210-4806(99)72389-2.
9
Extremely rare presentation of burned-out testicular tumor.睾丸肿瘤消退期的极其罕见表现。
Int J Health Sci (Qassim). 2018 May-Jun;12(3):94-95.
10
Burned-Out Testicular Germ Cell Tumor Presenting as Retroperitoneal Lymphadenopathy in a Patient With Cryptorchidism: A Case Report & Review of Literature.隐睾症患者中以腹膜后淋巴结病为表现的消退型睾丸生殖细胞肿瘤:一例报告及文献复习
Cureus. 2022 Jul 12;14(7):e26776. doi: 10.7759/cureus.26776. eCollection 2022 Jul.

引用本文的文献

1
Remarkable Response to Cisplatin-Based Chemotherapy and Long-Term Remission in a Young Male with Widespread Extragonadal Choriocarcinoma: A Case Report and Literature Review.一名患有广泛性腺外绒毛膜癌的年轻男性对基于顺铂的化疗有显著反应并长期缓解:病例报告及文献综述
Case Rep Oncol. 2025 Jun 12;18(1):949-957. doi: 10.1159/000546751. eCollection 2025 Jan-Dec.
2
Primary Undifferentiated Neoplasm of the Left Arm with Characteristics of Extragonadal Germ Cell Tumor and High-Grade Sarcoma.左臂原发性未分化肿瘤,具有性腺外生殖细胞肿瘤和高级别肉瘤的特征。
Clin Oncol Case Rep. 2023 Feb;6(2). Epub 2023 Feb 18.
3
Burned-out germ cell tumor presenting with acute abdomen.

本文引用的文献

1
"Burned out" phenomenon of the testis in retroperitoneal seminoma.腹膜后精原细胞瘤中睾丸的“萎缩”现象
Acta Oncol. 2006;45(3):335-6. doi: 10.1080/02841860500401175.
2
'Burned-out' primary testicular cancer.“消退型”原发性睾丸癌
BJU Int. 2004 Jul;94(1):74-8. doi: 10.1111/j.1464-410X.2004.04904.x.
3
Lesions of testes observed in certain patients with widespread choriocarcinoma and related tumors. The significance and genesis of hematoxylin-staining bodies in the human testis.在某些患有广泛绒毛膜癌及相关肿瘤的患者中观察到的睾丸病变。人睾丸中苏木精染色小体的意义及起源。
以急性腹痛为表现的耗竭性生殖细胞肿瘤。
Ulus Travma Acil Cerrahi Derg. 2022 Nov;28(11):1650-1654. doi: 10.14744/tjtes.2021.68792.
4
Metastatic testicular cancer presenting with hematuria and flank pain.以血尿和胁腹疼痛为表现的转移性睾丸癌。
Urol Ann. 2022 Apr-Jun;14(2):196-198. doi: 10.4103/UA.UA_63_20. Epub 2022 Apr 18.
5
'Burned-out' syndrome of testicular teratoma: A case report.睾丸畸胎瘤“消退”综合征:一例报告
Mol Clin Oncol. 2021 Dec;15(6):262. doi: 10.3892/mco.2021.2424. Epub 2021 Oct 22.
6
Spontaneous testicular tumor regression: case report and historical review.自发性睾丸肿瘤消退:病例报告及历史回顾
Ecancermedicalscience. 2018 Dec 18;12:888. doi: 10.3332/ecancer.2018.888. eCollection 2018.
7
Brain Metastases as Presenting Feature in 'Burned Out' Testicular Germ Cell Tumor.脑转移作为“消退型”睾丸生殖细胞肿瘤的首发特征
Cureus. 2016 Apr 1;8(4):e551. doi: 10.7759/cureus.551.
8
Burned out seminomatous testicular tumor with retroperitoneal lymph node metastasis: a case report.伴有腹膜后淋巴结转移的精原细胞瘤性睾丸肿瘤坏死:病例报告
Indian J Surg Oncol. 2013 Dec;4(4):390-2. doi: 10.1007/s13193-012-0207-6. Epub 2013 Jan 24.
Am J Pathol. 1961 Feb;38(2):207-25.
4
Extragonadal retroperitoneal germ cell tumor: evidence of origin in the testis.性腺外腹膜后生殖细胞肿瘤:起源于睾丸的证据。
Ann Oncol. 2002 Jan;13(1):121-4. doi: 10.1093/annonc/mdf003.
5
Burned-out primary testicular cancer: sonographic and pathological characteristics.原发性睾丸癌消退期:超声及病理特征
J Urol. 1996 Jul;156(1):85-8.
6
Extragonadal seminoma involving urinary bladder and arising in the prostate.发生于前列腺、累及膀胱的性腺外精原细胞瘤。
Cancer. 1993 Jun 15;71(12):3972-4. doi: 10.1002/1097-0142(19930615)71:12<3972::aid-cncr2820711228>3.0.co;2-p.
7
Burned-out tumour of the testis presenting as retroperitoneal choriocarcinoma.表现为腹膜后绒毛膜癌的睾丸萎缩性肿瘤。
Int Urol Nephrol. 1994;26(5):549-53. doi: 10.1007/BF02767657.
8
Ultrasonographic detection of "burned-out" primary testicular germ cell tumors in clinically normal testes.超声检查对临床正常睾丸中“消退型”原发性睾丸生殖细胞肿瘤的检测
J Ultrasound Med. 1983 Oct;2(10):477-9. doi: 10.7863/jum.1983.2.10.477.
9
Testicular seminoma metastatic to the prostate.睾丸精原细胞瘤转移至前列腺。
J Urol. 1986 Apr;135(4):801-2. doi: 10.1016/s0022-5347(17)45860-5.
10
Primary or secondary extragonadal germ cell tumors?原发性或继发性性腺外生殖细胞肿瘤?
J Urol. 1986 May;135(5):939-43. doi: 10.1016/s0022-5347(17)45930-1.