Department of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Ocul Immunol Inflamm. 2009 Sep-Oct;17(5):364-9. doi: 10.3109/09273940903105110.
To investigate the management strategies, susceptibility patterns, and visual outcomes of postcataract Enterococcus faecalis endophthalmitis.
Retrospective chart review study of 26 eyes of 26 patients with culture-proven E. faecalis endophthalmitis.
In initial treatments, pars plana vitrectomy with intravitreal antibiotics in 15 eyes (58%). Resistance patterns among the isolates were the following: vancomycin in 0 of 26 eyes (0%), ampicillin in 0 of 26 eyes (0%), teicoplanin in 0 of 18 eyes (0%), and high-level gentamicin (minimum inhibitory concentration > 500 mg/L) in 8 of 12 eyes (67%). Presenting visual acuity ranged from counting fingers to no light perception. Final visual acuity was better than 5/200 in 4 of 26 eyes (15%), 5/200 to hand motions in 4 of 26 eyes (15%), and light perception to no light perception in 18 of 26 eyes (69%).
Although all E. faecalis isolates were susceptible to vancomycin, endophthalmitis caused by E. faecalis was usually associated with poor visual prognosis.
研究白内障术后粪肠球菌性眼内炎的治疗策略、药敏模式和视力结局。
对 26 例（26 只眼）培养证实的粪肠球菌性眼内炎患者的病历进行回顾性分析。
在初始治疗中，15 只眼（58%）行玻璃体切除术联合眼内注射抗生素。分离株的耐药模式如下：26 只眼中无万古霉素耐药（0%），26 只眼中无氨苄西林耐药（0%），18 只眼中无替考拉宁耐药（0%），12 只眼中有 8 只（67%）对高浓度庆大霉素（最低抑菌浓度>500mg/L）耐药。就诊时视力从指数至无光感。最终视力>20/500 的有 4 只眼（15%），20/500 至手动视力的有 4 只眼（15%），光感至无光感的有 18 只眼（69%）。
尽管所有粪肠球菌分离株均对万古霉素敏感，但粪肠球菌性眼内炎通常与较差的视力预后相关。
