Biological Science Laboratories, Kao Corporation, Tochigi, Japan.
Skin Res Technol. 2009 Nov;15(4):384-91. doi: 10.1111/j.1600-0846.2009.00375.x.
BACKGROUND/PURPOSE: Since there is no standard protocol that specifies the opening or closing of eyelids in wrinkle assessment, the eyelid position of subjects at the time of assessment varies from study to study. This study aimed to reveal the effect of eye opening and closing on the result of wrinkle assessment. The study also attempted to analyze the age-, site-, and ethnicity-dependent variations in the effect.
Open- and closed-eyed photographs were obtained from 87 Japanese women of ages ranging from 21 to 73 years, and also from 80 American women comprising of Asians, Caucasians, Africans and Hispanics in their 30s. Their wrinkle intensities were scored separately at nine facial sites using a five-point photo scale. The obtained scores were compared between open- and closed-eyed photographs. The differences were then compared across age- and ethnic-groups.
In Japanese subjects, a significant difference was found at the forehead wrinkle in all age groups, and also at the glabella, nasal root and eye corner in the middle and old age groups. In American subjects, significant differences were found at the forehead, nasal root, eye-corner, and upper and lower eyelids. The differences were more prominent in the Hispanic and Caucasian Americans than in the Asian and African Americans.
These results suggest that the eyelid position should be considered as a variable in wrinkle assessment.
背景/目的：由于在皱纹评估中没有指定睁眼或闭眼的标准协议，因此评估时受试者的眼睑位置因研究而异。本研究旨在揭示睁眼和闭眼对皱纹评估结果的影响。该研究还试图分析年龄、部位和种族依赖性变化的影响。
从年龄在 21 至 73 岁的 87 名日本女性和 80 名 30 多岁的亚洲人、白种人、非洲人和西班牙裔美国人中获取睁眼和闭眼照片。使用五分制照片量表在九个面部部位分别对皱纹强度进行评分。将获得的分数与睁眼和闭眼照片进行比较。然后，比较不同年龄组和种族组之间的差异。
在日本受试者中，所有年龄组的额部皱纹差异均有统计学意义，中年和老年组的眉间、鼻根和眼角皱纹差异也有统计学意义。在美国受试者中，前额、鼻根、眼角、上下眼睑均有显著差异。西班牙裔和白种美国人的差异比亚洲人和非裔美国人更为明显。
这些结果表明，在皱纹评估中应考虑眼睑位置作为一个变量。
