Head and Neck Unit, Royal Marsden NHS Foundation Trust and Institute of Cancer Research, London, UK.
Clin Oncol (R Coll Radiol). 2009 Dec;21(10):737-44. doi: 10.1016/j.clon.2009.09.002. Epub 2009 Oct 14.
Radiation-induced xerostomia is highly prevalent among patients treated for head and neck cancers. Consequently, survivors experience associated long-term toxicities that may be grouped as xerostomia syndrome: dry mouth, sore throat, altered taste, dental decay, changes in voice quality and impaired chewing and swallowing function. We present a review of published studies describing and reporting xerostomia and discuss advances made in the prevention and treatment of this common toxicity.
放疗引起的口干症在头颈部癌症治疗患者中非常普遍。因此,幸存者会经历与之相关的长期毒性反应,这些毒性反应可能被归类为口干症综合征:口干、喉咙痛、味觉改变、龋齿、声音质量变化以及咀嚼和吞咽功能受损。我们回顾了已发表的描述和报告口干症的研究,并讨论了预防和治疗这种常见毒性反应的进展。