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放射性口干症:病理生理学、预防和治疗。

Radiation-induced xerostomia: pathophysiology, prevention and treatment.

机构信息

Head and Neck Unit, Royal Marsden NHS Foundation Trust and Institute of Cancer Research, London, UK.

出版信息

Clin Oncol (R Coll Radiol). 2009 Dec;21(10):737-44. doi: 10.1016/j.clon.2009.09.002. Epub 2009 Oct 14.

DOI:10.1016/j.clon.2009.09.002
PMID:19833490
Abstract

Radiation-induced xerostomia is highly prevalent among patients treated for head and neck cancers. Consequently, survivors experience associated long-term toxicities that may be grouped as xerostomia syndrome: dry mouth, sore throat, altered taste, dental decay, changes in voice quality and impaired chewing and swallowing function. We present a review of published studies describing and reporting xerostomia and discuss advances made in the prevention and treatment of this common toxicity.

摘要

放疗引起的口干症在头颈部癌症治疗患者中非常普遍。因此,幸存者会经历与之相关的长期毒性反应,这些毒性反应可能被归类为口干症综合征:口干、喉咙痛、味觉改变、龋齿、声音质量变化以及咀嚼和吞咽功能受损。我们回顾了已发表的描述和报告口干症的研究,并讨论了预防和治疗这种常见毒性反应的进展。

相似文献

1
Radiation-induced xerostomia: pathophysiology, prevention and treatment.放射性口干症:病理生理学、预防和治疗。
Clin Oncol (R Coll Radiol). 2009 Dec;21(10):737-44. doi: 10.1016/j.clon.2009.09.002. Epub 2009 Oct 14.
2
Pathophysiology and management of radiation-induced xerostomia.放射性口干症的病理生理学与管理
J Support Oncol. 2005 May-Jun;3(3):191-200.
3
Evaluation, prevention and management of radiotherapy-induced xerostomia in head and neck cancer patients.头颈部癌患者放疗所致口干症的评估、预防及管理
Curr Opin Oncol. 2006 May;18(3):266-70. doi: 10.1097/01.cco.0000219256.37843.83.
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Patients with head and neck cancer cured by radiation therapy: a survey of the dry mouth syndrome in long-term survivors.经放射治疗治愈的头颈癌患者:长期幸存者口干综合征的调查
Head Neck. 2002 Aug;24(8):737-47. doi: 10.1002/hed.10129.
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The prevention and treatment of radiotherapy - induced xerostomia.放射治疗引起的口干症的防治
Semin Radiat Oncol. 2003 Jul;13(3):302-8. doi: 10.1016/S1053-4296(03)00027-4.
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Using technology to decrease xerostomia for head and neck cancer patients treated with radiation therapy.利用技术减少接受放射治疗的头颈癌患者的口干症。
Semin Oncol. 2002 Dec;29(6 Suppl 19):71-9. doi: 10.1053/sonc.2002.37353.
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A critical component of supportive care.支持性护理的一个关键组成部分。
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[Side effects of radiotherapy in oral cavity: diagnosis, prevention and treatment guidelines].[口腔放疗的副作用:诊断、预防及治疗指南]
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