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接受支架置入术或带补片血管成形术的内膜切除术的患者,其术后颈动脉的形态学和血流动力学状况存在显著差异。

Significant differences in the postoperative morphological and hemodynamic conditions of carotid arteries of patients undergoing stenting or endarterectomy with patch angioplasty.

作者信息

Tokunaga Koji, Sugiu Kenji, Hayase Hitoshi, Nishida Ayumi, Date Isao

机构信息

Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

出版信息

Neurosurgery. 2009 Nov;65(5):884-8; discussion 888-9. doi: 10.1227/01.NEU.0000358952.12917.DF.

Abstract

OBJECTIVE

Carotid endarterectomy with a patch graft (Patch CEA) has been our standard treatment for patients with carotid artery stenosis, but carotid artery stenting (CAS) has emerged as an alternative. The purpose of this study was to compare the postoperative changes in the configurations and the flow velocities of carotid arteries after CAS or Patch CEA.

METHODS

Thirty-one patients undergoing CAS or Patch CEA were included. The pre- and postoperative shapes of the carotid arteries were evaluated by angiography and ultrasonography. Doppler waveforms were recorded in the middle portion of the common carotid artery and in the internal carotid artery bulb to measure flow velocities, including peak systolic, mean, and end-diastolic velocities.

RESULTS

Eighteen patients were treated by CAS, and Patch CEA was performed for 13 patients. Preoperatively, there were no differences in the degrees of stenosis or the flow velocities between the 2 groups. The averages of the diameters of the postoperative internal carotid artery bulbs were 4.5 mm in the CAS group and 7.0 mm in the Patch CEA group (P < 0.01). The averages of peak systolic, mean, and end-diastolic velocities measured in the internal carotid artery were 80, 42, and 25 cm/s, respectively, in the CAS group, and were significantly greater than those (53, 28, and 16 cm/s, respectively) in the Patch CEA group (P < 0.01).

CONCLUSION

Significant differences in postoperative morphological and hemodynamic conditions between CAS and Patch CEA were observed. The impact of these differences will be determined by further studies.

摘要

目的

带补片的颈动脉内膜切除术(补片CEA)一直是我们治疗颈动脉狭窄患者的标准方法,但颈动脉支架置入术(CAS)已成为一种替代方法。本研究的目的是比较CAS或补片CEA术后颈动脉形态和血流速度的变化。

方法

纳入31例行CAS或补片CEA的患者。通过血管造影和超声检查评估颈动脉术前和术后的形态。在颈总动脉中部和颈内动脉球部记录多普勒波形,以测量血流速度,包括收缩期峰值、平均和舒张末期速度。

结果

18例患者接受了CAS治疗,13例患者接受了补片CEA治疗。术前,两组间狭窄程度和血流速度无差异。CAS组术后颈内动脉球部平均直径为4.5mm,补片CEA组为7.0mm(P<0.01)。CAS组颈内动脉测量的收缩期峰值、平均和舒张末期速度平均值分别为80、42和25cm/s,显著高于补片CEA组的(分别为53、28和16cm/s)(P<0.01)。

结论

观察到CAS和补片CEA术后形态学和血流动力学状况存在显著差异。这些差异的影响将通过进一步研究确定。

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