Boos C, Hohlbach G, Reusche E, Richter P
Chirurgische Klinik, Medizinischen Universität zu Lübeck.
Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir. 1990:435-6.
The effect of intraoperative local fibrinolysis after delayed catheterembolectomy (CE) of occluded arteries was examined in a model in the dogs hind limb; the superficial femoral artery was occluded by a rapid injection of an autologeous blood clot and ligation. Embolectomy was performed 24 h after occlusion with or without additional local fibrinolysis (urocinase, r-tPA). The success of revascularisation was estimated by measurement of the total periphereal resistance. There happened a total re-occlusion in all vessels within 48 h if only CE was performed; in contrast after additional fibrinolysis a complete revascularisation could be achieved.
在犬后肢模型中研究了延迟性导管取栓术（CE）治疗闭塞动脉后术中局部纤溶的效果；通过快速注射自体血凝块并结扎使股浅动脉闭塞。在闭塞24小时后进行取栓术，同时进行或不进行额外的局部纤溶（尿激酶、重组组织型纤溶酶原激活剂）。通过测量总外周阻力评估血管再通的成功情况。如果仅进行CE，所有血管在48小时内都会完全再次闭塞；相比之下，在进行额外纤溶后可实现完全血管再通。
