Department of Medicine (Cardiology), Namazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
J Am Soc Echocardiogr. 2010 Mar;23(3):341.e3-5. doi: 10.1016/j.echo.2009.09.004. Epub 2009 Oct 15.
The most common valves involved in systemic lupus erythematosus are the mitral and aortic valves. Although isolated tricuspid valve involvement is quite rare, the authors report such a case. A 42-year-old woman presented with exertional dyspnea and was found to have a cardiac murmur. Echocardiography showed a stenotic tricuspid valve with vegetations on all 3 cusps. No other valvular vegetation could be detected. Concomitant tricuspid regurgitation was noted too. Blood culture results were negative. Clinical findings and serologic tests confirmed the diagnosis of systemic lupus erythematosus. The patient was successfully treated with prednisolone and hydroxychloroquine, and follow-up echocardiography showed the disappearance of the vegetations.
系统性红斑狼疮最常累及的瓣膜为二尖瓣和主动脉瓣。虽然孤立性三尖瓣受累相当罕见,但作者报告了这样一个病例。一位 42 岁女性因劳力性呼吸困难就诊,发现心脏杂音。超声心动图显示三尖瓣狭窄,所有 3 个瓣叶均有赘生物。未发现其他瓣叶赘生物。同时存在三尖瓣反流。血培养结果为阴性。临床发现和血清学检查证实诊断为系统性红斑狼疮。患者经泼尼松龙和羟氯喹治疗后病情得到缓解,随访超声心动图显示赘生物消失。