下颌骨基底样鳞状细胞癌：2例报告

Basaloid squamous cell carcinoma of the mandible: report of two cases.

作者信息

Hirai Eiji, Yamamoto Kozo, Yamamoto Noriaki, Yamashita Yoshihiro, Kounoe Toshiaki, Kondo Yoshihide, Yonemasu Hirotoshi, Takahashi Tetsu, Kurokawa Hideo

机构信息

Department of Oral and Maxillofacial Surgery, Oita Red Cross Hospital, Oita, Japan.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Nov;108(5):e54-8. doi: 10.1016/j.tripleo.2009.07.011.

DOI:10.1016/j.tripleo.2009.07.011

PMID:19836714

Abstract

Basaloid squamous cell carcinoma is a rare aggressive malignancy that is a distinct variant of squamous cell carcinoma. This report presents 2 cases of basaloid squamous cell carcinoma in the gingiva. Case 1 is a 55-year-old Japanese man who presented with a painful, red, and irregular mass on the left mandibular gingiva. Case 2 is a 65-year-old Japanese man who presented with a painless mass on the right mandibular gingiva. Both tumors were diagnosed histopathologically as basaloid squamous cell carcinoma. In case 1, the patient underwent wide resection of the gingival tumor with a partial mandibulectomy and ipsilateral functional neck dissection. The mandible was reconstructed with a titanium plate and forearm flap. In case 2, the patient underwent wide resection of the gingival tumor after local irradiation (60 Gy). At the time of writing, both patients remained in good health and free of disease.

摘要

基底样鳞状细胞癌是一种罕见的侵袭性恶性肿瘤，是鳞状细胞癌的一种独特变体。本报告介绍了2例牙龈基底样鳞状细胞癌病例。病例1是一名55岁的日本男性，其左下颌牙龈出现一个疼痛、红色且不规则的肿块。病例2是一名65岁的日本男性，其右下颌牙龈出现一个无痛肿块。这两个肿瘤经组织病理学诊断均为基底样鳞状细胞癌。在病例1中，患者接受了牙龈肿瘤广泛切除术，并行部分下颌骨切除术和同侧功能性颈清扫术。下颌骨用钛板和前臂皮瓣重建。在病例2中，患者在局部照射（60 Gy）后接受了牙龈肿瘤广泛切除术。在撰写本文时，两名患者均保持健康，无疾病复发。