一条新的延髓通路的激活引发豚鼠迷走神经介导的胆碱能性支气管收缩。
Activation of a novel medullary pathway elicits a vagal, cholinergic bronchoconstriction in guinea-pigs.
作者信息
Hey J A, del Prado M, Chapman R W
机构信息
Department of Allergy and Inflammation, Schering-Plough Research, New Jersey 07003.
出版信息
Pulm Pharmacol. 1990;3(1):53-4. doi: 10.1016/0952-0600(90)90010-g.
PMID:1983733
Abstract
Electrical stimulation of structures within the rostral region of the dorsal medulla of the guinea-pig activates a vagal cholinergic bronchoconstriction pathway and simultaneously activates a sympathetic inhibitory input. Removal of the latter by spinal section potentiated CNS-induced bronchospasm.
摘要
对豚鼠延髓背侧吻侧区域内的结构进行电刺激，会激活一条迷走胆碱能支气管收缩途径，同时激活一条交感抑制性传入神经。通过脊髓横断术去除后者会增强中枢神经系统诱导的支气管痉挛。
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