Sobesky J
Klinik für Neurologie und Center for Stroke Research (CSB), Charité Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland.
Internist (Berl). 2009 Nov;50(11):1218-26. doi: 10.1007/s00108-009-2470-3.
New diagnostic and therapeutic developments have led to an innovative approach to stroke therapy. The slogan "time is brain" emphasizes that stroke is a medical emergency comparable to myocardial infarction. The stroke unit conception is an evidence based therapy for all stroke patients and improves outcome significantly. The monitoring of vital signs and the management of stroke specific complications are highly effective. Early secondary prophylaxis reduces the risk of recurrence. The effect of CT based thrombolysis within the time window of 4,5 h has been substantiated by current data. Stroke MRI holds the promise for an improved therapy by patient stratification and by opening the time window. Interventional recanalisation, vascular interventions and hemicraniectomy complement the therapeutic options in the acute phase of stroke.
新的诊断和治疗进展带来了一种创新的中风治疗方法。“时间就是大脑”这一口号强调，中风是一种与心肌梗死相当的医疗急症。中风单元理念是针对所有中风患者的循证治疗方法，能显著改善治疗结果。生命体征监测和中风特异性并发症的管理非常有效。早期二级预防可降低复发风险。目前的数据证实了在4.5小时时间窗内基于CT的溶栓治疗效果。中风磁共振成像有望通过患者分层和延长时间窗来改善治疗。介入再通、血管介入和颅骨切除术补充了中风急性期的治疗选择。
