Department of Neurology, University of Mansoura, Mansoura, Egypt.
Acta Neurol Scand. 2010 Aug;122(2):97-101. doi: 10.1111/j.1600-0404.2009.01265.x. Epub 2009 Oct 15.
The onset of acute stroke exhibits a circadian pattern occurring more frequently in late morning hours. The objective of this study was to investigate the diurnal pattern of stroke during the month of Ramadan.
We studied consecutive stroke patients 1 month before Ramadan (BR) and during Ramadan (DR) over two successive years 2007 and 2008. The age, gender, risk factor profiles were analyzed. The National Institute of Health and Stroke Scale Score (NIHSS) was used for clinical assessment at admission. The exact time of stroke onset in both groups was obtained.
A total of 507 patients were studied: 245 patients in the DR group and 262 patients in the BR group. The age distribution of patients was not significantly different between the two groups. There was no statistically significant difference in the sex ratio, risk factors, and NIHSS score between the two groups (P > 0.05). The higher frequency of stroke onset time in the BR group was in the time between 6:00 a.m. and noon; whereas the frequency was higher between noon and 6:00 p.m. in the DR group.
A significant shift of the circadian pattern of stroke onset time from the period between 6:00 a.m. and noon to that between noon and 6:00 pm has been found during the month of Ramadan.
急性中风的发病呈现出一种昼夜节律模式，即在上午晚些时候更为常见。本研究旨在探讨斋月期间中风的昼夜节律模式。
我们连续 2 年（2007 年和 2008 年）在斋月（DR）期间和斋月前 1 个月（BR）连续研究了中风患者。分析了年龄、性别、危险因素谱。入院时使用国立卫生研究院和中风量表评分（NIHSS）进行临床评估。两组患者中风发病的确切时间均已获得。
共研究了 507 例患者：DR 组 245 例，BR 组 262 例。两组患者的年龄分布无显著差异。两组的性别比例、危险因素和 NIHSS 评分无统计学差异（P>0.05）。BR 组中风发病时间的频率更高是在上午 6:00 至中午之间；而在 DR 组，频率更高是在中午至下午 6:00 之间。
在斋月期间，中风发病时间的昼夜节律模式从上午 6:00 至中午之间明显转移到中午至下午 6:00 之间。
