Menon Santosh, Karpate Arti, Desai Sangeeta
Department of Pathology, Tata Memorial Hospital, Parel, Mumbai 400 012, India.
J Cancer Res Ther. 2009 Jul-Sep;5(3):213-5. doi: 10.4103/0973-1482.57131.
Spermatocytic seminoma is an uncommon testicular germ cell tumor associated with a favorable outcome. Sarcomatous transformation in a spermatocytic seminoma is extremely rare with only 13 cases being reported in English literature. The presence of a sarcomatous component is associated with an aggressive behavior, metastasis, and poor prognosis. We present a case of a spermatocytic seminoma with rhabdomyosarcomatous transformation in a long-standing testicular swelling in a 55-year-old male.
精母细胞性精原细胞瘤是一种罕见的睾丸生殖细胞肿瘤,预后良好。精母细胞性精原细胞瘤发生肉瘤样变极为罕见,英文文献中仅报道了13例。肉瘤样成分的存在与侵袭性生物学行为、转移及预后不良相关。我们报告一例55岁男性,其长期存在的睾丸肿大为精母细胞性精原细胞瘤伴横纹肌肉瘤样变。