Pandey Vinita, Khatib Yasmeen, Khade Archana Laxman, Pandey Rahul, Khare Manisha S
Department of Pathology, HBT Medical College and Dr. R. N. Cooper Hospital, Mumbai, Maharashtra, India.
Department of Pathology, HBT Medical College and Dr. R. N. Cooper Municipal General Hospital, Mumbai, Maharashtra, India.
Indian J Pathol Microbiol. 2018 Jul-Sep;61(3):437-439. doi: 10.4103/IJPM.IJPM_243_17.
Spermatocytic seminoma (SCS) is an indolent germ cell tumor of the testis. It has an excellent prognosis and orchidectomy is generally curative. Very rarely, it can be complicated by a sarcomatous transformation which is associated with a very aggressive behavior and requires adjuvant therapy. SCS with sarcomatous component is a very rare occurrence with <20 cases described in the world literature of which eight showed rhabdomyoblastic differentiation. We report a case of SCS with rhabdomyosarcomatous differentiation in a 60-year-old male along with a short review of literature.
精母细胞性精原细胞瘤(SCS)是一种睾丸惰性生殖细胞肿瘤。其预后极佳,睾丸切除术通常可治愈。极罕见情况下,它可并发肉瘤样转化,这与极具侵袭性的行为相关,需要辅助治疗。伴有肉瘤成分的SCS非常罕见,世界文献中报道的病例不足20例,其中8例显示有横纹肌母细胞分化。我们报告一例60岁男性患有伴有横纹肌肉瘤分化的SCS病例,并对相关文献进行简要综述。