Kinge Einar, Ulfberg Jan
Sandvika Nevrosenter, 1337 Sandvika, Norway.
Tidsskr Nor Laegeforen. 2009 Sep 24;129(18):1888-91. doi: 10.4045/tidsskr.09.0042.
Restless legs syndrome is a common cause of sleep problems; the condition is often associated with periodic limb movement during sleep. The syndrome is probably under-diagnosed and under-treated.
The article is based on literature identified through a search in PubMed, a review of international recommendations and our own clinical experience.
The restless leg syndrome is common, with a prevalence of about 10 %. Many of these patients are affected by sleep disturbances and have periodic limb movement during sleep (PLMS). Restless legs and the associated sleep disturbances can be effectively treated with dopaminagonists. Because of the augmentation risk, the lowest necessary dose should be maintained. PLMS also occurs in other sleep disorders. Periodic limb movement disorder (PLMD) is defined as PLMS combined with sleep disturbances and/or sleepiness during daytime without a known cause. The clinical relevance of PLMD for sleep disturbances is not clear.
The restless legs syndrome is a common cause of sleep disturbance; good treatment options are available.
不宁腿综合征是睡眠问题的常见原因;该病症常与睡眠期间的周期性肢体运动相关。该综合征可能未得到充分诊断和治疗。
本文基于通过在PubMed上搜索所确定的文献、对国际建议的综述以及我们自己的临床经验。
不宁腿综合征很常见,患病率约为10%。这些患者中的许多人受到睡眠障碍的影响,并且在睡眠期间有周期性肢体运动(PLMS)。不宁腿及相关的睡眠障碍可用多巴胺能激动剂有效治疗。由于存在症状加重的风险,应维持最低必要剂量。PLMS也发生于其他睡眠障碍中。周期性肢体运动障碍(PLMD)定义为PLMS合并睡眠障碍和/或白天不明原因的嗜睡。PLMD对睡眠障碍的临床相关性尚不清楚。
不宁腿综合征是睡眠障碍的常见原因;有良好的治疗选择。