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成人潜在器官捐献者的管理:脑死亡后的捐献(第 1 部分)。

How I manage the adult potential organ donor: donation after neurological death (part 1).

机构信息

Mount Sinai School of Medicine, New York, NY, USA.

出版信息

Neurocrit Care. 2010 Feb;12(1):103-10. doi: 10.1007/s12028-009-9292-y.

Abstract

The need for organ donation has become a growing concern over that last decade as the gap between organ donors and those awaiting transplant widens. According to UNOS, as of 8/2009, there were 102,962 patients on the transplant waiting list and only 6,004 donors in 2009 (UNOS.org. Accessed 4/8/2009). In 2008, an estimated 17 patients died each day awaiting transplant (OPTN.org). Though currently most organ donations come after brain death (DND or donation after neurological death), tissue donation (cornea, skin, bone, and musculoskeletal tissue), and donation after cardiac death (DCD) and are also possible. The term "extended criteria donor" refers to potential donors over 60 years of age or age 50-59 years plus 2 of the 3 following criteria: stroke as the cause of death, creatnine > 1.5 meq/dl, or a history of hypertension. Historically, extended criteria donors have had a lower organ yield per donor. In order to preserve the choice of organ donation for the family, intensive management of the potential organ donor is necessary. Since each potential donor could save seven lives or more, nihilism in the care of such patients can have far reaching ramifications. This article describes intensive care management practices that can optimize organ donation.

摘要

在过去的十年中,由于器官捐献者与等待移植者之间的差距不断扩大,器官捐献的需求成为人们日益关注的问题。根据 UNOS 的数据,截至 2009 年 8 月,有 102962 名患者在移植等待名单上,而 2009 年仅 6004 人捐献器官(UNOS.org。访问日期:2009 年 4 月 8 日)。2008 年,每天估计有 17 名患者在等待移植时死亡(OPTN.org)。尽管目前大多数器官捐献来自脑死亡(DND 或死后神经捐献)、组织捐献(角膜、皮肤、骨骼和肌肉骨骼组织)和心脏死亡后捐献(DCD),但也有可能。“扩展标准供体”一词是指年龄超过 60 岁或 50-59 岁加 3 个以下标准中的 2 个的潜在供体:死亡原因是中风、肌酐 > 1.5 meq/dl 或高血压病史。从历史上看,扩展标准供体的每个供体器官的产量较低。为了保留家庭对器官捐献的选择,有必要对潜在器官捐献者进行强化管理。由于每个潜在的捐献者都可以拯救七个或更多的生命,因此对这些患者的护理的虚无主义可能会产生深远的影响。本文介绍了可以优化器官捐献的强化护理管理实践。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/533e/7091387/b1b1cb0175c9/12028_2009_9292_Fig1_HTML.jpg

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