Liang Jian-feng, Tian Rong, Feng Li
Intensive Care Unit, Beijing Geriatric Hospital, Beijing 100095, China.
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2009 Oct;21(10):617-20.
To compare the spontaneous breathing trial (SBT) weaning mode with the classical weaning mode for extubation in patients undergoing mechanical ventilation.
Fifty-seven patients showing stabilized condition after mechanical ventilation, were divided into two groups. In 21 patients, admitted from June 2004 to December 2005, a gradual decrease in respiratory support as the mode of weaning of mechanical ventilation. In 36 patients, admitted from January 2006 to March 2007, SBT weaning mode was adopted. The length of mechanical ventilation and stay in intensive care unit (ICU), ventilator-associated pneumonia (VAP) rate, retubing rate in 48 hours, ICU mortality were compared between two groups.
The length of mechanical ventilation were (59.4+/-37.1) hours and (111.4+/-59.8) hours (P=0.001), length of stay in ICU were (8.0+/-5.5) days and (15.3+/-14.3) days (P=0.034), VAP rate was 16.7% and 38.0% (P=0.070), retubing rate in 48 hours were 19.4% and 5.0% (P=0.253), ICU mortality rate was 25.0% and 24.0% (P=0.920) in SBT group and control group, respectively.
The SBT weaning mode shortens the time of mechanical ventilation and the ICU stay days. Both groups have the identical VAP rate, retubing rate in 48 hours, and ICU mortality.
比较机械通气患者脱机时自主呼吸试验（SBT）撤机模式与传统撤机模式。
57例机械通气后病情稳定的患者分为两组。21例于2004年6月至2005年12月入院，采用逐渐降低呼吸支持的方式作为机械通气撤机模式。36例于2006年1月至2007年3月入院，采用SBT撤机模式。比较两组患者的机械通气时间、重症监护病房（ICU）住院时间、呼吸机相关性肺炎（VAP）发生率、48小时内再插管率、ICU死亡率。
SBT组和对照组的机械通气时间分别为（59.4±37.1）小时和（111.4±59.8）小时（P = 0.001），ICU住院时间分别为（8.0±5.5）天和（15.3±14.3）天（P = 0.034），VAP发生率分别为16.7%和38.0%（P = 0.070），48小时内再插管率分别为19.4%和5.0%（P = 0.253），ICU死亡率分别为25.0%和24.0%（P = 0.920）。
SBT撤机模式缩短了机械通气时间和ICU住院天数。两组的VAP发生率、48小时内再插管率和ICU死亡率相同。
