Nace E P, Davis C W, Gaspari J P
Timberlawn Psychiatric Hospital, Dallas, TX 75223.
Am J Psychiatry. 1991 Jan;148(1):118-20. doi: 10.1176/ajp.148.1.118.
To assess the complex relationship between substance abuse and personality disorders, the authors determined the prevalence of personality disorders in a group of middle-class substance abusers and compared the subjects who had personality disorders with those who did not.
The subjects were drawn from patients consecutively admitted to an inpatient substance abuse program in a private psychiatric hospital; they were the first 100 who agreed to participate. Substance dependence was diagnosed according to DSM-III-R, and the patients were assessed with the Structured Clinical Interview for DSM-III-R Personality Disorders, Alcohol Use Inventory, MMPI, Health and Daily Living Form, Shipley Institute of Living Scale, and measures of chemical use and life satisfaction.
Of the 100 substance abusers, 57 had personality disorders. These patients differed significantly from the 43 patients without personality disorders in several ways: they had greater involvement with illegal drugs, had different patterns of alcohol use, had greater psychopathology, were less satisfied with their lives, and were more impulsive, isolated, and depressed.
Because of the marked differences between the substance abusers with and without personality disorders, a uniform approach to substance abuse treatment may be inadequate.
为评估药物滥用与人格障碍之间的复杂关系,作者测定了一组中产阶级药物滥用者中人格障碍的患病率,并将患有人格障碍的受试者与未患有人格障碍的受试者进行了比较。
受试者来自一家私立精神病医院连续收治的住院药物滥用项目患者;他们是首批同意参与的100人。根据《精神疾病诊断与统计手册》第三版修订本(DSM-III-R)诊断药物依赖,并使用《DSM-III-R人格障碍结构化临床访谈》、《酒精使用量表》、《明尼苏达多相人格调查表》、《健康与日常生活表格》、《希普利生活量表》以及药物使用和生活满意度测量工具对患者进行评估。
在100名药物滥用者中,57人患有人格障碍。这些患者在几个方面与43名未患人格障碍的患者有显著差异:他们更多地涉及非法药物,有不同的饮酒模式,有更严重的精神病理学问题,对生活不太满意,且更冲动、孤立和抑郁。
由于患有人格障碍和未患人格障碍的药物滥用者之间存在明显差异,统一的药物滥用治疗方法可能并不充分。