Larsen Signe, Bendtzen Klaus, Nielsen Ole Haagen
c/o Ole Haagen Nielsen, Gastroenheden, Medicinsk Sektion, Herlev Hospital, Herlev Ringvej 75, DK-2730 Herlev, Denmark.
Ugeskr Laeger. 2009 Oct 19;171(43):3078-83.
Extraintestinal manifestations are relatively common in chronic inflammatory bowel disease and affect joints, skin, eyes and bile ducts. The most frequent rheumatologic manifestations are peripheral arthritis and axial arthropathies. Erythema nodosum and pyoderma gangraenosum are common dermatological manifestations, while episcleritis, iridocyclitis and uveitis are common ophthalmological complications. Conventional drugs and biologicals have proven effective in the treatment of several of the manifestations, including peripheral arthritis, pyoderma gangraenosum and episcleritis.
肠外表现在慢性炎症性肠病中相对常见,可累及关节、皮肤、眼睛和胆管。最常见的风湿性表现为外周关节炎和轴性关节病。结节性红斑和坏疽性脓皮病是常见的皮肤表现,而巩膜外层炎、虹膜睫状体炎和葡萄膜炎是常见的眼科并发症。传统药物和生物制剂已被证明对包括外周关节炎、坏疽性脓皮病和巩膜外层炎在内的多种表现有效。