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脊柱融合术对杜氏肌营养不良症呼吸功能的影响。

The effect of spine fusion on respiratory function in Duchenne muscular dystrophy.

作者信息

Miller R G, Chalmers A C, Dao H, Filler-Katz A, Holman D, Bost F

机构信息

Department of Neurology, Children's Hospital of San Francisco, CA 94119.

出版信息

Neurology. 1991 Jan;41(1):38-40. doi: 10.1212/wnl.41.1.38.

DOI:10.1212/wnl.41.1.38
PMID:1985293
Abstract

Serial measures of respiratory function were made in 17 patients with Duchenne muscular dystrophy who underwent segmental spine fusion and in 22 patients who did not. No significant differences were observed between the 2 groups (operated vs. nonoperated) in terms of declining respiratory function. Nonetheless, all operated patients reported either improved sitting comfort, appearance, or both. Thus, our results suggest that there are distinct benefits from segmental spine fusion; however, there was no salutary effect upon respiratory function either in the short term or after up to 5 years follow-up.

摘要

对17例接受节段性脊柱融合术的杜氏肌营养不良患者和22例未接受该手术的患者进行了呼吸功能的系列测量。两组(手术组与非手术组)在呼吸功能下降方面未观察到显著差异。尽管如此,所有接受手术的患者均报告坐姿舒适度、外观或两者均有改善。因此,我们的结果表明节段性脊柱融合术有明显益处;然而,无论是短期还是长达5年的随访后,对呼吸功能均无有益影响。

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