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杜氏肌营养不良症脊柱手术的长期结果

Long-term results of spine surgery in Duchenne muscular dystrophy.

作者信息

Granata C, Merlini L, Cervellati S, Ballestrazzi A, Giannini S, Corbascio M, Lari S

机构信息

Neuromuscular Spine Centre, Toniolo Hospital, Bologna, Italy.

出版信息

Neuromuscul Disord. 1996 Jan;6(1):61-8. doi: 10.1016/0960-8966(95)00019-4.

DOI:10.1016/0960-8966(95)00019-4
PMID:8845720
Abstract

We report the long-term orthopaedic and functional results of segmental spinal instrumentation and fusion in 30 Duchenne patients. Twenty-nine had a mean 59% correction of scoliosis with post-operative immobilization in a brace of only three months on average and with a very limited loss of correction over time. One died after cardiac arrest. The mean vital capacity preoperatively was 57 +/- 17% with a decrease to 34 +/- 13% at 3.9 +/- 2 yr after surgery. The sitting position, aesthetic improvement and the quality of life after spinal fusion have been positively evaluated by the large majority of the patients and their parents. Head control was lost in the 14 patients who developed a more severe extension contracture of the neck measured as a significantly longer chin-sternum distance. More than 90% would have the operation or would give their consent again for their son having the operation.

摘要

我们报告了30例杜氏患者进行节段性脊柱内固定和融合术的长期骨科及功能结果。29例患者平均脊柱侧弯矫正率为59%,术后仅平均佩戴支具三个月,且随着时间推移矫正丢失非常有限。1例患者因心脏骤停死亡。术前平均肺活量为57±17%,术后3.9±2年降至34±13%。绝大多数患者及其父母对脊柱融合术后的坐姿、美观改善及生活质量给予了积极评价。14例患者因颈部严重伸展挛缩(通过显著更长的颏胸骨距离测量)而失去头部控制能力。超过90%的患者表示会接受手术或会再次同意儿子接受手术。

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Long-term results of spine surgery in Duchenne muscular dystrophy.杜氏肌营养不良症脊柱手术的长期结果
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