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1547名高中生中抑郁症状、绝望感与自杀意念之间的关系

[Relationship between depressive symptoms, hopelessness and suicidal ideation among 1547 high school students].

作者信息

Chabrol H, Choquet M

机构信息

Centre D'études et de Recherches en Psychopathologie, Université de Toulouse Le Mirail, pavillon de la recherche, 5, allées Antonio-Machado, 31058 Toulouse cedex 9, France.

出版信息

Encephale. 2009 Oct;35(5):443-7. doi: 10.1016/j.encep.2008.10.010. Epub 2009 Mar 6.

Abstract

OBJECTIVES

The aim of the study was to evaluate the incidence of depressive symptoms and suicidal ideation, and to test the mediating role of hopelessness between depressive symptoms and the wish to kill oneself.

METHOD

A random sample of 1547 high school students from the department of Haute-Garonne, France, (854 girls, mean age=16.9+/-1.5; 693 boys, mean age=17.4+/-1.5) completed a questionnaire assessing cannabis use, the Center for Epidemiological Studies-Depression Scale (CES-D) completed by the three items subscale measuring suicidal ideation proposed by Garrison et al. (1991) ("I felt life was not worth living"; "I felt like hurting myself"; "I felt like killing myself"). The measure of hopelessness was based on a single item, "I felt life was not worth living".

RESULTS

At least occasional wish to kill oneself were reported by 13% of boys and 14% of girls (NS). The mean CES-D score for girls was significantly higher than for boys (20.3+/-10.7 versus 16.7+/-9.9; p<0.01). According to the cut-off score of 24, 19% of boys and 34% of girls had a moderate to severe depressive symptomatology (p<0.0001). The mean suicidal ideation score was significantly higher in participants scoring 24 or above on the CES-D than participants scoring less than 24 (2.4+/-2.7 versus 0.3+/-0.9; p<0.0001). Among participants with CES-D greater or equal to 24, 34% reported at least occasional wish to kill oneself versus 6% of participants with CES-D less than 24 (p<0.0001). CES-D scores and suicidal ideation scores were moderately correlated in girls (Pearson's r=0.59) and boys (r=0.61) in the total sample. To explore the role of hopelessness as mediator between depressive symptoms and the wish to kill oneself, multiple regression analyses were performed separately by gender. To establish mediation, three regression equations should be estimated and the four following conditions must hold: First, the independent variable (CES-D scores) must affect the mediator in the first equation; second, the independent variable must affect the dependent variable (the wish to kill oneself) in the second equation; third, the mediator must affect the dependent variable in the third equation regressing the dependent variable on both the independent variable and on the mediator; fourth, the effect of the independent variable on the dependent variable must be less in the third equation than in the second. Among girls, in the first equation, CES-D score explained 35% of the variance of hopelessness (beta=0.59, t=21.5, p<0.001). In the second equation, CES-D score explained 16% of the variance in the wish to kill oneself (beta=0.40, t=12.7, p<0.001). In the third equation, CES-D and hopelessness scores explained 32% of the variance in the wish to kill oneself. Hopelessness was the main predictor (beta=0.50, t=14, p<0.001) while the effect of CES-D was markedly reduced (beta=0.10, t=2.9, p<0.01). Among boys, in the first equation, CES-D score explained 38% of the variance of hopelessness (beta=0.62, t=20.7, p<0.001). In the second equation, CES-D score explained 25% of the variance in the wish to kill oneself (beta=0.50, t=15.1, p<0.001). In the third equation, CES-D and hopelessness scores explained 47% of the variance in the wish to kill oneself. Hopelessness was the main predictor (beta=0.60, t=17, p<0.001) while the effect of CES-D was substantially weakened (beta=0.13, t=3.6, p<0.001).

DISCUSSION

These results showed a strong association between depressive symptoms and suicidal ideation in this nonclinical sample of adolescents. According to Beck's assumption, hopelessness appeared to be a mediator between depressive symptoms and the wish to kill oneself both in boys and girls. These findings are relevant for prevention and therapy. They suggest that targeting hopelessness may be as important in adolescents as in adults to reduce suicidal ideation and prevent suicidal attempts.

摘要

目的

本研究旨在评估抑郁症状和自杀意念的发生率,并检验绝望感在抑郁症状与自杀意愿之间的中介作用。

方法

从法国上加龙省随机抽取1547名高中生作为样本(854名女生,平均年龄 = 16.9 ± 1.5岁;693名男生,平均年龄 = 17.4 ± 1.5岁),他们完成了一份评估大麻使用情况的问卷,以及由Garrison等人(1991年)提出的用于测量自杀意念的包含三个项目的流行病学研究中心抑郁量表(CES - D)(“我觉得生活不值得活下去”;“我想伤害自己”;“我想自杀”)。绝望感的测量基于一个单项,即“我觉得生活不值得活下去”。

结果

报告至少偶尔有自杀意愿的男生占13%,女生占14%(无显著差异)。女生的CES - D平均得分显著高于男生(20.3 ± 10.7对16.7 ± 9.9;p < 0.01)。根据24分的临界值,19%的男生和34%的女生有中度至重度抑郁症状(p < 0.0001)。CES - D得分在24分及以上的参与者的自杀意念平均得分显著高于得分低于24分的参与者(2.4 ± 2.7对0.3 ± 0.9;p < 0.0001)。在CES - D大于或等于24分的参与者中,34%报告至少偶尔有自杀意愿,而CES - D小于24分的参与者中这一比例为6%(p < 0.0001)。在整个样本中,女生和男生的CES - D得分与自杀意念得分呈中度相关(女生Pearson相关系数r = 0.59,男生r = 0.61)。为了探究绝望感作为抑郁症状和自杀意愿之间中介的作用,按性别分别进行了多元回归分析。为了确定中介作用,应估计三个回归方程,且必须满足以下四个条件:第一,在第一个方程中自变量(CES - D得分)必须影响中介变量;第二,在第二个方程中自变量必须影响因变量(自杀意愿);第三,在第三个方程中,当将因变量同时对自变量和中介变量进行回归时,中介变量必须影响因变量;第四,在第三个方程中自变量对因变量的影响必须小于第二个方程中的影响。在女生中,在第一个方程中,CES - D得分解释了绝望感方差的35%(β = 0.59,t = 21.5,p < 0.001)。在第二个方程中,CES - D得分解释了自杀意愿方差的16%(β = 0.40,t = 12.7,p < 0.001)。在第三个方程中,CES - D和绝望感得分解释了自杀意愿方差的32%。绝望感是主要预测因素(β = 0.50,t = 14,p < 0.001),而CES - D的影响显著降低(β = 0.10,t = 2.9,p < 0.01)。在男生中,在第一个方程中,CES - D得分解释了绝望感方差的38%(β = 0.62,t = 20.7,p < 0.001)。在第二个方程中,CES - D得分解释了自杀意愿方差的25%(β = 0.50,t = 15.1,p < 0.001)。在第三个方程中,CES - D和绝望感得分解释了自杀意愿方差的47%。绝望感是主要预测因素(β = 0.60,t = 17,p < 0.001),而CES - D的影响大幅减弱(β = 0.13,t = 3.6,p < 0.001)。

讨论

这些结果表明,在这个非临床青少年样本中,抑郁症状与自杀意念之间存在强烈关联。根据贝克的假设,绝望感似乎在男生和女生中都是抑郁症状与自杀意愿之间的中介因素。这些发现对于预防和治疗具有重要意义。它们表明,针对绝望感对于青少年减少自杀意念和预防自杀企图可能与成年人同样重要。

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