Cincinnati Children's Hospital Medical Center, University of Cincinnati, William Rowe Division of Rheumatology, Cincinnati, OH 45229-3039, USA.
Best Pract Res Clin Rheumatol. 2009 Oct;23(5):609-24. doi: 10.1016/j.berh.2009.07.001.
This review provides a theoretical background and approach for developing outcome measures that are often used to assess the state and course of paediatric rheumatic diseases. It describes the important steps in scale development such as item generation and reduction, the assessment of scale reliability and various forms of validation. The second part of this review described the newly developed outcome measures as well as their state of validation. These outcome measures include therapeutic response measures, composite disease activity scores for juvenile idiopathic arthritis (JIA), global disease activity tools for juvenile systemic lupus erythematosus and juvenile dermatomyositis, disease status measures in JIA, measures of physical function, measures of health-related quality of life, clinical measures of damage and radiographic scoring systems in JIA.
这篇综述为开发常用于评估儿科风湿性疾病状态和病程的结局测量指标提供了理论背景和方法。它描述了量表开发的重要步骤，如项目生成和删减、量表信度评估以及各种形式的验证。本综述的第二部分描述了新开发的结局测量指标及其验证状态。这些结局测量指标包括治疗反应测量指标、幼年特发性关节炎（JIA）的综合疾病活动评分、幼年系统性红斑狼疮和幼年皮肌炎的整体疾病活动工具、JIA 的疾病状态测量指标、身体功能测量指标、健康相关生活质量测量指标、JIA 的临床损伤测量指标和放射学评分系统。
